Fig. 4. Structure-activity relationships of rivulariapeptolides and molassamides.
a Structures of the isolated rivulariapeptolides 1185 (1), 1155 (2), 1121 (3), 988 (4); red = residues defined in panel c. b Structures of the isolated known molassamide (5), and the new molassamide B (6). c Potency of isolated compounds for selected serine proteases following 40 min pre-incubations. Data were presented as the mean ± SD, n = 3. Ba butyric acid, Pro proline. Source data are provided as a Source Data file.