TABLE 3.
Delayed-match-to-sample – delayed recognition performance by baseline memory function.
| #Subjects | Positive stim | NoStim | Negative stim | %Change positive stim | %Change negative stim | |
| ALL STIM | ||||||
| Impaired | 12 | 75.5% ± 3.9% | 61.9% ± 5.1% | 56.4% ± 6.4% | 22.0% | –8.8% |
| Normal | 12 | 83.0% ± 3.5% | 76.1% ± 4.3% | 75.9% ± 5.2% | 9.1% | –0.3% |
| MDM STIM | ||||||
| Impaired | 9 | 77.8% ± 4.6% | 65.2% ± 5.9% | 63.7% ± 4.9% | 19.3% | –2.4% |
| Normal | 10 | 80.9% ± 4.1% | 71.4% ± 5.5% | 73.9% ± 6.4% | 13.4% | 3.6% |
| MIMO STIM | ||||||
| Impaired | 5 | 73.1% ± 5.2% | 54.9% ± 6.8% | 40.3% ± 10.9% | 33.2% | –26.6% |
| Normal | 6 | 88.2% ± 3.2% | 77.1% ± 6.4% | 73.3% ± 6.6% | 14.5% | –4.9% |
Stimulated and non-stimulated task performance by baseline memory function for subjects receiving CA1 stimulation based on MDM and MIMO models. Positive stim = stimulation patterns derived from modeling correct DMS trials (MIMO) or from MDM patterns that were congruent with the content classification of the Sample/Match image. NoStim = trials with no stimulation delivered. Negative stim = trials with random stimulation patterns (MIMO) or from MDM that were not specific to the content classification of the Sample/Match image). Stimulation was only delivered during the Sample phase of DMS trials, and not delivered during Match phase, nor during the DR assessment. %Change = percentage of increase (+, no symbol) or decrease (–) compared to NoStim.