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. 2022 Jul 25;16:933401. doi: 10.3389/fnhum.2022.933401

TABLE 3.

Delayed-match-to-sample – delayed recognition performance by baseline memory function.

#Subjects Positive stim NoStim Negative stim %Change positive stim %Change negative stim
ALL STIM
Impaired 12 75.5% ± 3.9% 61.9% ± 5.1% 56.4% ± 6.4% 22.0% –8.8%
Normal 12 83.0% ± 3.5% 76.1% ± 4.3% 75.9% ± 5.2% 9.1% –0.3%
MDM STIM
Impaired 9 77.8% ± 4.6% 65.2% ± 5.9% 63.7% ± 4.9% 19.3% –2.4%
Normal 10 80.9% ± 4.1% 71.4% ± 5.5% 73.9% ± 6.4% 13.4% 3.6%
MIMO STIM
Impaired 5 73.1% ± 5.2% 54.9% ± 6.8% 40.3% ± 10.9% 33.2% –26.6%
Normal 6 88.2% ± 3.2% 77.1% ± 6.4% 73.3% ± 6.6% 14.5% –4.9%

Stimulated and non-stimulated task performance by baseline memory function for subjects receiving CA1 stimulation based on MDM and MIMO models. Positive stim = stimulation patterns derived from modeling correct DMS trials (MIMO) or from MDM patterns that were congruent with the content classification of the Sample/Match image. NoStim = trials with no stimulation delivered. Negative stim = trials with random stimulation patterns (MIMO) or from MDM that were not specific to the content classification of the Sample/Match image). Stimulation was only delivered during the Sample phase of DMS trials, and not delivered during Match phase, nor during the DR assessment. %Change = percentage of increase (+, no symbol) or decrease (–) compared to NoStim.