Table 2.

Cell subset frequencies in BS patients and in healthy controls

Parent population	Subset	BS patients (n = 23)	Healthy controls (n = 28)	p-value
Lymphocyte	CD4+ T cells	36.5 ± 10.8%	37.4 ± 7.0%	0.80
	Naïve CD4+ T cells	16.8 ± 8.6%	17.7 ± 6.7%	0.55
	Memory CD4+ T cells	16.3 ± 7.3%	15.8 ± 5.0%	0.90
	CD8+ T cells	16.7% ± 7.0%	14.0 ± 5.0%	0.13
	Naïve CD8+ T cells	9.1 ± 5.4%	8.4 ± 4.7%	0.86
	Memory CD8+ T cells	7.6 ± 4.4%	5.7 ± 2.3%	0.19
	B cells	11.3 ± 6.7%	10.8 ± 3.8%	0.94
	Natural killer cells	12.5 ± 10.8%	11.9 ± 6.5%	0.45
B cells	Naïve B cells	69.6 ± 21.5%	73.2 ± 8.6%	0.60
	Unswitched memory B cells	7.9 ± 8.1%	7.3 ± 3.5%	0.19
	Switched memory B cells	16.0 ± 12.4%	14.3 ± 5.4%	0.65
	Plasmablasts	1.7 ± 2.6%	1.1 ± 1.0%	0.86
	Double negative B cells	3.7 ± 2.6%	3.4 ± 1.6%	0.79
CD4+ T cells	Th1 cells	9.2 ± 5.1%	13.1 ± 5.4%	0.003
	Th2 cells	11.7 ± 5.5%	9.7 ± 4.6%	0.11
	Th17 cells	9.5 ± 4.9%	5.4 ± 2.4%	< 0.0001
	T follicular helper cells	4.9 ± 3.1%	6.5 ± 3.4%	0.11
	Fraction II effector regulatory T cells	1.4 ± 0.5%	1.3 ± 0.4%	0.34
Lymphocyte and monocyte gate	Monocytes	18.6 ± 9.9%	13.4 ± 6.5%	0.06
	CD16+ monocytes	1.6 ± 1.1%	1.4 ± 0.9%	0.66
	CD16− monocytes	17.0 ± 9.1%	11.9 ± 6.1%	0.06
	Dendritic cells	0.7 ± 0.3%	0.7 ± 0.3%	0.60
	Myeloid dendritic cells	0.5 ± 0.2%	0.5 ± 0.2%	0.34
	Plasmacytoid dendritic cells	0.2 ± 0.1%	0.2 ± 0.1%	0.63

Nominal p-values from Mann-Whitney’s U test are indicated