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. 2022 Aug 8;22:139. doi: 10.1186/s12880-022-00864-9

Table 6.

Results of multivariate logistic regression models for differentiating stage IA EC from BELs

Models Coefficients Odds ratio 95% CI p value
Clinical model
 Age at diagnosis, years
  ≤ 50 Reference
  51–64 1.412 4.106 2.269–7.429 < 0.001
  ≥ 65 0.574 1.776 0.563–5.604 0.328
 Nulliparity
  No Reference
  Yes 1.433 4.191 1.066–16.472 0.040
 Long-term Tamoxifen therapy
  No Reference
  Yes − 1.963 0.14 0.038–0.524 0.003
ADC histogram model
 ADC10th − 3.270 0.038 0.016–0.092 < 0.001
 rMAD − 0.710 0.492 0.271–0.893 0.020
 Total energy 1.025 2.788 1.416–5.490 0.003
 Skewness 0.605 1.832 1.155–2.907 0.010
Combined model
 ADC-score* 0.971 2.641 2.045–3.411 < 0.001
 Age at diagnosis, years
  ≤ 50 Reference
  51–64 0.711 2.036 0.821–5.046 0.125
  ≥ 65 1.623 5.068 0.905–28.383 0.065
 Nulliparity
  No Reference
  Yes 0.446 1.562 0.252–9.670 0.631
 Long-term Tamoxifen therapy
  No Reference
  Yes − 0.846 0.429 0.061–2.996 0.393

rMAD, robust mean absolute deviation

*ADC-score = 0.257 + − 3.270 × ADC10th + − 0.710 × rMAD + 1.025 × Total_Energy + 0.605 × Sknewness. All ADC histogram features were standardized by Z-score normalization