Table 5.
Physical and chemical indexes by gender and osteoporosis diagnose.
| Total | Normal | Osteopenia | Osteoporosis | P value | P value by LSD | |
| Male (N=364) | ||||||
| Height (cm) | 170.01 ± 5.80 | 171.79 ± 5.70 | 170.33 ± 5.38 | 166.77 ± 5.95 | <0.001* | 0.038@, <0.001#, <0.001$ |
| Weight (kg) | 73.15 ± 11.14 | 75.07 ± 14.81 | 73.97 ± 9.36 | 67.89 ± 8.56 | <0.001* | <0.001#, <0.001$ |
| BMI (kg/cm2) | 25.29 ± 3.52 | 25.48 ± 4.90 | 25.48 ± 2.93 | 24.41 ± 2.77 | 0.083 | |
| Waistline (cm) | 90.15 ± 16.80 | 92.81 ± 15.74 | 89.85 ± 18.23 | 87.27 ± 12.60 | 0.128 | |
| Hipline (cm) | 99.38 ± 16.83 | 102.37 ± 15.35 | 98.51 ± 18.30 | 97.89 ± 13.17 | 0.148 | |
| W/H | 0.91 ± 0.08 | 0.91 ± 0.07 | 0.91 ± 0.09 | 0.89 ± 0.06 | 0.211 | |
| Grip strength of left hand (Kg) | 32.73 ± 8.88 | 36.04 ± 9.68 | 31.82 ± 8.42 | 31.01 ± 8.03 | <0.001* | <0.001@, <0.001# |
| Grip strength of right hand (Kg) | 34.35 ± 8.67 | 37.35 ± 7.55 | 33.51 ± 8.99 | 32.77 ± 8.21 | 0.001* | <0.001@, 0.001# |
| Sit test (S) | 9.30 ± 4.26 | 8.63 ± 2.76 | 9.48 ± 3.73 | 9.65 ± 6.75 | 0.050 | |
| Alkaline phosphatase-ALP (U/L) | 72.74 ± 22.33 | 68.60 ± 16.06 | 74.29 ± 24.68 | 73.70 ± 21.66 | 0.126 | |
| Creatinine (μmol/L) | 82.14 ± 15.25 | 84.45 ± 14.20 | 81.34 ± 14.13 | 81.40 ± 19.46 | 0.255 | |
| Parathyroid hormone-PTH (pmol/L) | 3.10 ± 1.21 | 3.01 ± 1.13 | 3.06 ± 1.23 | 3.34 ± 1.23 | 0.191 | |
| Osteocalcin-OST (ng/mL) | 10.75 ± 3.88 | 9.74 ± 3.19 | 10.78 ± 3.93 | 12.10 ± 4.21 | 0.001* | 0.034@, <0.001#, 0.017$ |
| Serum Phosphorus (mol/L) | 1.23 ± 0.22 | 1.22 ± 0.23 | 1.23 ± 0.23 | 1.22 ± 0.21 | 0.927 | |
| Serum Magnesium (mmol/L) | 0.93 ± 0.80 | 0.93 ± 0.80 | 0.93 ± 0.82 | 0.94 ± 0.72 | 0.598 | |
| Serum Total Calcium (mmol/L) | 2.35 ± 0.85 | 2.36 ± 0.08 | 2.35 ± 0.09 | 2.34 ± 0.08 | 0.271 | |
| β-CTx (ng/mL) | 0.24 ± 0.11 | 0.20 ± 0.08 | 0.24 ± 0.11 | 0.28 ± 0.12 | <0.001* | 0.004@, <0.001#, 0.017$ |
| PINP (ng/mL) | 38.44 ± 15.05 | 33.97 ± 13.87 | 39.23 ± 15.04 | 42.22 ± 15.44 | 0.002* | 0.006@, 0.001# |
| 25-hydroxyvitamin D3 (ng/mL) | 15.41 ± 5.78 | 16.31 ± 5.97 | 15.10 ± 5.65 | 15.20 ± 5.83 | 0.231 | |
| 25-hydroxyvitamin D2 (ng/mL) | 3.49 ± 2.88 | 4.06 ± 3.36 | 3.51 ± 2.97 | 2.54 ± 1.24 | 0.304 | |
| 25-hydroxyvitamin D Total (ng/mL) | 16.20 ± 6.04 | 17.32 ± 6.32 | 15.85 ± 5.93 | 15.77 ± 5.86 | 0.304 | |
| Female (N=1055) | ||||||
| Height (cm) | 158.72 ± 5.64 | 160.53 ± 6.24 | 159.28 ± 5.29 | 157.36 ± 5.43 | <0.001* | 0.011@, <0.001#, <0.001$ |
| Weight (kg) | 63.09 ± 9.52 | 68.60 ± 9.50 | 64.14 ± 9.22 | 59.65 ± 8.46 | <0.001* | <0.001@, <0.001#, <0.001$ |
| BMI (kg/cm2) | 25.04 ± 3.56 | 26.64 ± 3.67 | 25.30 ± 3.57 | 24.09 ± 3.20 | <0.001* | <0.001@, <0.001#, <0.001$ |
| Waistline (cm) | 86.38 ± 52.53 | 87.28 ± 66.47 | 85.97 ± 39.14 | 86.45 ± 58.07 | 0.961 | |
| Hipline (cm) | 96.75 ± 18.97 | 96.30 ± 21.00 | 97.84 ± 20.42 | 95.77 ± 16.27 | 0.262 | |
| W/H | 0.89 ± 0.49 | 0.90 ± 0.59 | 0.88 ± 0.37 | 0.90 ± 0.55 | 0.830 | |
| Grip strength of left hand (Kg) | 22.35 ± 6.92 | 25.01 ± 6.58 | 22.88 ± 7.67 | 20.68 ± 5.67 | <0.001* | <0.001@, <0.001#, <0.001$ |
| Grip strength of right hand (Kg) | 23.22 ± 6.02 | 25.57 ± 6.10 | 23.51 ± 5.65 | 21.92 ± 6.04 | <0.001* | <0.001@, <0.001#, <0.001$ |
| Sit test (S) | 8.95 ± 3.57 | 8.17 ± 3.33 | 8.66 ± 2.89 | 9.61 ± 4.18 | <0.001* | 0.006@, <0.001#, 0.003$ |
| Alkaline phosphatase-ALP (U/L) | 78.75 ± 23.45 | 69.97 ± 20.33 | 77.88 ± 21.98 | 83.45 ± 25.01 | <0.001* | <0.001@, <0.001#, 0.001$ |
| Creatinine (μmol/L) | 62.95 ± 11.72 | 61.30 ± 9.63 | 63.12 ± 10.52 | 63.47 ± 11.72 | 0.114 | |
| Parathyroid hormone-PTH (pmol/L) | 3.41 ± 1.37 | 3.18 ± 1.24 | 3.37 ± 1.29 | 3.55 ± 1.48 | 0.009* | 0.003# |
| Osteocalcin-OST (ng/mL) | 14.18 ± 5.15 | 11.51 ± 3.60 | 13.93 ± 4.69 | 15.63 ± 5.67 | <0.001* | <0.001@, <0.001#, <0.001$ |
| Serum Phosphorus (mol/L) | 1.36 ± 0.21 | 1.36 ± 0.21 | 1.36 ± 0.20 | 1.35 ± 0.22 | 0.882 | |
| Serum Magnesium (mmol/L) | 0.93 ± 0.07 | 0.91 ± 0.07 | 0.93 ± 0.07 | 0.93 ± 0.08 | 0.019* | 0.015@, 0.007# |
| Serum Total Calcium (mmol/L) | 2.37 ± 0.08 | 2.37 ± 0.09 | 2.37 ± 0.08 | 2.37 ± 0.09 | 0.981 | |
| β-CTx (ng/mL) | 0.29 ± 0.12 | 0.23 ± 0.11 | 0.28 ± 0.11 | 0.32 ± 0.13 | <0.001* | <0.001@, <0.001#, <0.001$ |
| PINP (ng/mL) | 48.73 ± 19.97 | 41.60 ± 14.71 | 48.77 ± 18.73 | 51.80 ± 22.35 | <0.001* | <0.001@, <0.001#, 0.047$ |
| 25-hydroxyvitamin D3 (ng/mL) | 14.66 ± 5.77 | 14.89 ± 5.87 | 14.61 ± 5.56 | 14.60 ± 5.95 | 0.178 | |
| 25-hydroxyvitamin D2 (ng/mL) | 4.09 ± 4.81 | 4.90 ± 6.56 | 3.66 ± 3.71 | 4.29 ± 5.18 | 0.364 | |
| 25-hydroxyvitamin D Total (ng/mL) | 15.68 ± 6.25 | 15.85 ± 6.50 | 15.57 ± 6.05 | 15.73 ± 6.37 | 0.871 | |
values are presented as mean ± SD.
*: P<0.05 among the 3 groups (Normal, Osteopenia, and Osteoporosis) by ANOVA.
@: P<0.05 between the Normal group and the Osteopenia group;
#: P<0.05 between the Normal group and the Osteoporosis group;
$: P<0.05 between the Osteopenia group and the Osteoporosis group.
β-CTx stands for β cross-linked C-telopeptide of type 1 collagen; PINP represented Procollagen type 1 N-terminal propeptide.
The male case number involved in the tests of β-CTx, PINP, 25-hydroxyvitamin D3, and 25-hydroxyvitamin D Total was 357; and in the test of 25-hydroxyvitamin D2 is 80; The female case numbers in the above two parts are 1012 and 252, respectively.