Table 6.
Correlations of inflammatory mediators. Data from all subjects (healthy controls, mild/moderate and severe cases).
| Parameters | CRPn=260 | SAAn=260 | IL-6n=260 | IL-8n=260 | CXCL10n=260 | TNFαn=260 | IL-10n=260 | VEGF-Dn=260 | CCL22n=260 | VCAM-1n=260 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CRP | R-value P-value | 0.923 0.000 |
0.846 0.000 |
0.497 0.000 |
0.453 0.000 |
0.464 0.000 |
0.655 0.000 |
-0.059 0.343 |
-0.455 0.000 |
0.622 0.000 |
|
| SAA | R-value P-value |
0.923 0.000 |
0.797 0.000 |
0.442 0.000 |
0.707 0.000 |
0.441 0.000 |
0.656 0.000 |
-0.059 0.340 |
-0.458 0.000 |
0.610 0.000 |
|
| IL-6 | R-value P-value |
0.846 0.000 |
0.797 0.000 |
0.506 0.000 |
0.636 0.000 |
0.479 0.000 |
0.706 0.000 |
0.010 0.868 |
-0.437 3.730E-014 |
0.630 0.000 |
|
| IL-8 | R-value P-value |
0.497 0.000 |
0.442 0.000 |
0.506 0.000 |
0.453 0.000 |
0.413 4.593E-012 |
0.434 1.033E-013 |
-0.013 0.843 |
-0.292 0.000 |
0.407 1.132E-011 |
|
| CXCL10 | R-value P-value |
0.453 0.000 |
0.707 0.000 |
0.636 0.00 |
0.453 0.000 |
0.624 0.000 |
0.679 0.000 |
-0.208 0.001 |
-0.343 0.000 |
0.614 0.000 |
|
| TNF-α | R-value P-value |
0.464 0.000 |
0.441 0.000 |
0.479 0.000 |
0.413 4.593E-012 |
0.624 0.000 |
0.518 0.000 |
-0.243 0.000 |
-0.154 0.013 |
0.587 0.000 |
|
| IL-10 | R-value P-value |
0.655 0.000 |
0.656 0.000 |
0.706 0.000 |
0.434 1.033E-013 |
0.679 0.000 |
0.518 0.000 |
-0.105 0.092 |
-0.438 1.799E-014 |
0.575 0.000 |
|
| VEGF-D | R-value P-value |
-0.059 0.343 |
-0.059 0.34 |
0.010 0.868 |
-0.013 0.843 |
-0.208 0.001 |
-0.243 0.000 |
-0.105 0.092 |
0.032 0.605 |
-0.011 0.854 |
|
| CCL22 | R-value P-value |
-0.455 0.000 |
-0.458 0.000 |
-0.437 3.730E-014 |
-0.292 0.000 |
-0.343 0.000 |
-0.154 0.013 |
-0.438 1.799E-014 |
0.032 0.605 |
-0.375 0.000 |
|
| VCAM-1 | R-value P-value |
0.622 0.000 |
0.610 0.000 |
0.630 0.000 |
0.407 1.132E-011 |
0.614 0.000 |
0.587 0.000 |
0.575 0.000 |
-0.011 0.854 |
0.375 0.000 |
|
The pair(s) of variables with positive correlation coefficients and P values below 0.05 tend to increase together. For the pairs with negative correlation coefficients and P values below 0.05, one variable tends to decrease while the other increases. For pairs with P values greater than 0.05, there is no significant linear relationship between the two variables.