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. 2022 Jul 25;13:955390. doi: 10.3389/fimmu.2022.955390

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Copyright © 2022 Liu, Zhang, Ju, Wang and Qie

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Determination of the expression and prognostic role of SPP1 and CD44 in HCC. (A) The mRNA expression of SPP1 and CD44 in HCC from the TCGA-LIHC database. (B) IHC staining of SPP1 and CD44 in normal and HCC tissues from HPA database. (C) The correlation of the expression of SPP1 and CD44 in HCC (n = 424) from TCGA-LIHC database. (D, E) Kaplan–Meier survival curve of SPP1 and CD44 in HCC from TCGA-LIHC database. HCC, hepatocellular carcinoma; TCGA-LIHC, The Cancer Genome Atlas Liver Hepatocellular Carcinoma; IHC, immunohistochemistry; HPA, Human Protein Atlas.