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. Author manuscript; available in PMC: 2022 Aug 9.
Published in final edited form as: FASEB J. 2020 Jun 27;34(8):10027–10040. doi: 10.1096/fj.202000312R

FIGURE 4.

FIGURE 4

In vivo thrombosis. A, In vivo thrombus formation was studied in the carotid artery in response to exposure to 5% FeCl3 for 3 minutes. The time to occlusion was quantified in control mice and platelet-COX-1-ko mice under control conditions or following treatment with aspirin (10 mg/kg, i.v.). The data are means ± SEM, n = 6–8 mice per group. *P < .05 (one-way ANOVA followed by Tukey’s post hoc test). B, Traces of blood flow rate in carotid arteries during thrombosis model in (blue line) control mice and (red line) platelet-COX-1-ko mice