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. 2022 Jul 25;12:913815. doi: 10.3389/fcimb.2022.913815

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Copyright © 2022 Wang, Liu, Xu, Wang, Wang, Zhang, Ni, Zhen, Xu, Liu, Fang, Huang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LINC00152 is involved in the S. typhimurium-introduced inflammation and cancer cell invasion and migration. (A) The expression level of LINC00152 in the control and overexpressed stalely cells. (B) LINC00152 overexpressed cells had fewer internalized Salmonella. (C) The number of bacteria attachment with cells in control and LINC00152-overexpressed cells. (D, E) The expression level of IL-8 and TNF α were reduced in the LINC00152 overexpressed cells compared with control HCT116 cells infected with S. typhimurium. (F) The migration and invasion of LINC00152 overexpressed HCT116 cells. All experiments were in three replicates. *P < 0.05; **P < 0.01; ***P < 0.001; n.s: not significant.