Table 2.
Genotype | AD Dementia (n = 382) | Cognitively normal (n = 2,197) | Total (n = 2,579) |
E2/2 | 3 (0.79%) | 18 (0.82%) | 21 (0.81%) |
E2/3 | 30 (7.85%) | 279 (12.70%) | 309 (11.98%) |
E2/4 | 17 (4.45%) | 43 (1.96%) | 60 (2.33%) |
E3/3 | 199 (52.09%) | 1,442 (65.64%) | 1,641 (63.63%) |
E3/4 | 124 (32.46%) | 391 (17.80%) | 515 (19.97%) |
E4/4 | 9 (2.36%) | 24 (1.09%) | 33 (1.28%) |
Hardy-Weinberg p | 0.079 | 0.878 | 0.402 |
Allele frequency | |||
APOE*2 | 0.0694 | 0.0815 | 0.0797 |
APOE*3 | 0.7225 | 0.8089 | 0.7961 |
APOE*4 | 0.2082 | 0.1097 | 0.1243 |