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. 2022 Jul 19;88(2):787–798. doi: 10.3233/JAD-220293

Table 2.

APOE genotype distribution

Genotype AD Dementia (n = 382) Cognitively normal (n = 2,197) Total (n = 2,579)
E2/2 3 (0.79%) 18 (0.82%) 21 (0.81%)
E2/3 30 (7.85%) 279 (12.70%) 309 (11.98%)
E2/4 17 (4.45%) 43 (1.96%) 60 (2.33%)
E3/3 199 (52.09%) 1,442 (65.64%) 1,641 (63.63%)
E3/4 124 (32.46%) 391 (17.80%) 515 (19.97%)
E4/4 9 (2.36%) 24 (1.09%) 33 (1.28%)
Hardy-Weinberg p 0.079 0.878 0.402
Allele frequency
APOE*2 0.0694 0.0815 0.0797
APOE*3 0.7225 0.8089 0.7961
APOE*4 0.2082 0.1097 0.1243