Table 1.

Summary of the neurofilament light chain (NfL) prototype and laboratory-developed test (LDT) assays' key differences.

	Prototype	LDT*
Instrument	ADVIA Centaur XP	Atellica Solution IM 1300
Assay throughput	Up to 75 tests per hour	Up to 171 tests per hour
Specimen types tested	Serum	Serum, plasma (K2 EDTA and lithium heparin), CSF

^*Available only as a test service through the Siemens Healthcare Laboratory.