Table 4.

Cross-reactivity assessment.

Test substance	Concentration (pg/mL)	% Cross-reactivity
		Target 0 pg/mL NfL-depleted serum	Target 7.65 pg/mL (Endogenous level 1)	Target 17.23 pg/mL (Endogenous level 2)	Target 438.03 pg/mL (Recombinant level 3)
NfM	1,000	ND	0.0146%	0.0380%	0.3705%
NfH	1,000	ND	0.0233%	0.0011%	0.6780%

ND was reported when the concentration difference between test and control samples is below the LoD. LoD, limit of detection; ND, not detectable; NfH, neurofilament heavy chain; NfM, neurofilament medium chain.