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. Author manuscript; available in PMC: 2022 Aug 9.
Published in final edited form as: Biol Psychiatry. 2020 Jul 1;89(5):497–509. doi: 10.1016/j.biopsych.2020.06.021

Figure 6.

Figure 6.

CRISPR–Cas9 knockout RNA-Seq analysis. Significant GO terms from gene set enrichment analysis of RNA-Seq datasets for knockouts of CHRNA7 (A), KLF13 (B), FAN1 (C), MTMR10 (D), and OTUD7A (E) are shown. The top 10 terms in each category based on FDR are listed, ordered by NES. *GO term also enriched in 15q13.3 microdeletion induced neurons. CRISPR, clustered regularly interspaced short palindromic repeats; FDR, false discovery rate; GO, Gene Ontology; ncRNA, noncoding RNA; NES, normalized enrichment score; NF, nuclear factor; RNA-Seq, RNA sequencing; rRNA, ribosomal RNA; snoRNA, small nucleolar RNA.