Table 1:

Detailed Baseline and Post-treatment Data

Animal #	Site	Target Energy Dose	No. of Pulses Delivered	Peak Heart Rate (bpm)	Blood Pressure S/D/M (mmHg)	AERP HRA (ms)	AERP CS (ms)	AERP LAA (ms)
1	Baseline	N/A	N/A	113	79/51/60	80	120	130
	OSGP	1000 V 100 μs	10 × 3	121	152/110/124	60	120	130
	RSGP	1000 V 100 μs	10 × 3	142	182/141/155	50	120	170
	TSGP	1000 V 100 μs	10 × 3	111	163/112/129	50	120	170
	LSGP	1000 V 100 μs	10 × 3	127	174/137/149	60	120	170
	LMGP	1000 V 100 μs	10 × 3	121	127/93/104	70	120	190
2	Baseline	N/A	N/A	104	75/45/55	60	100*	60
	OSGP	1000 V 100 μs	10 × 3	108	102/68/79	60	130	90*
	RSGP	1000 V 100 μs	10 × 3	162	111/74/86	90*	130	120*
	TSGP	1000 V 100 μs	10 × 3	164	110/77/88	50	90	110
	LSGP	1000 V 100 μs	10 × 3	141	82/58/66	60	110	100
	LMGP	1000 V 100 μs	10 × 3	138	125/86/99	80	130	120
3	Baseline	N/A	N/A	117	81/67/72	70	80	130
	OSGP	1000 V 100 μs	10 × 6	111	240/172/195	100	80	140
	RSGP	1000 V 100 μs	10 × 6	128	238/168/191	110	110	130
	TSGP	1000 V 100 μs	10 × 6	123	195/148/164	130	120	130
	LSGP	1000 V 100 μs	10 × 6	133	182/142/155	100	100	160
	LMGP	1000 V 100 μs	10 × 6	122	162/126/138	110	90	140
4	Baseline	N/A	N/A	94	106/63/77	90	120	90
	OSGP	1000 V 100 μs	10 × 6	107	156/120/132	120	150	110
	RSGP	1000 V 100 μs	10 × 6	116	145/111/122	130	130	90
	TSGP	1000 V 100 μs	10 × 6	114	139/113/122	120	110	100
	LSGP	1000 V 100 μs	10 × 6	98	129/120/123	120	120	150
	LMGP	1000 V 100 μs	10 × 6	84	124/98/106	100	130	120
5	Baseline	N/A	N/A	152	80/55/63	120	100	110
	OSGP	1000 V 100 μs	10 × 6	137	81/56/64	140	130	150
	RSGP	1000 V 100 μs	10 × 6	128	95/54/68	170	100	120
	TSGP	1000 V 100 μs	10 × 6	142	110/72/85	150	100	130
	LSGP	1000 V 100 μs	10 × 6	144	101/62/75	130	100	140
	LMGP	1000 V 100 μs	10 × 6	149	96/65/75	110	110	110

Abbreviations: AERP, atrial effective refractory period; CS, coronary sinus; HRA, high right atrium; LAA, left atrial appendage; LMGP, ligament of Marshall ganglionated plexi; LSGP, left superior ganglionated plexi; OSGP, oblique sinus ganglionated plexi; RSGP, right superior ganglionated plexi; S/D/M, systolic/diastolic/mean; TSGP, transverse sinus ganglionated plexi. Vital signs and atrial effective refractory period response are stratified by each experimental animal and each energy delivery site. *Denotes values that were likely higher than the actual AERP due to pacing-induced arrhythmia interfering with interpretation.