Table 1.
Summary chart of vaccine against COVID-19, with way of functioning.
| Type | Developer | Way of Functioning | |
|---|---|---|---|
| BNT162b2 | mRNA vaccine | Pfizer-BioNTech | The mRNA vaccine is delivered in a lipid nanoparticle to express a full-length spike protein |
| mRNA-1273 | mRNA vaccine | Moderna | The mRNA vaccine is delivered in a lipid nanoparticle to express a full-length spike protein |
| ChAdOx1 nCoV-19/AZD1222 | Replication-incompetent vector vaccine | University of Oxford, AstraZeneca, the Serum Institute of India | A replication-incompetent chimpanzee adenovirus vector that expresses the spike protein |
| Ad26.COV2.S | Replication-incompetent vector vaccine | Janssen/Johnson & Johnson | A replication-incompetent adenovirus 26 vector that encodes a stabilized spike protein |
| Gam-COVID-Vac/Sputnik V | Replication-incompetent vector vaccine | Gamaleya Institute | Two replication-incompetent adenovirus vectors that express a full-length spike glycoprotein |
| NVX-CoV2373 | Recombinant protein vaccine | Novavax | Recombinant protein subunit vaccine composed of trimeric spike glycoproteins and a potent Matrix-M1 adjuvant |
| CoronaVac | Inactivated vaccine | Sinovac | Produced by growing SARS-CoV-2 in cell culture then chemically inactivating the virus combined with an aluminum hydroxide adjuvant |
| Ad5-based COVID-19 vaccine | Replication-incompetent vector vaccine | CanSino | A replication-incompetent adenovirus 5 vector that expresses the spike protein |
| Covaxin | Inactivated vaccine | Bharat Biotech | Produced by growing SARS-CoV-2 in cell culture then chemically inactivating the virus combined with an aluminum hydroxide and a toll-like receptor agonist adjuvant |
| WIBP-CorV | Inactivated vaccine | Sinopharm | Produced by growing SARS-CoV-2 in cell culture then chemically inactivating the virus combined with an aluminum hydroxide adjuvant |
| BBIBP-CorV/HB02 | Inactivated vaccine | Covilo, Sinopharm | Produced by growing SARS-CoV-2 in cell culture then chemically inactivating the virus combined with an aluminum hydroxide adjuvant |
| ZyCoV-D | DNA vaccine | Zydus Cadila | A DNA plasmid vector pVAX1 carrying gene-expressing spikeS protein of SARS-CoV-2 and IgE signal peptide |