Table E2.

Case definition of immunization stress-related response (ISRR) in sensitivity analyses

Symptoms/signs	Initial	ISRR-2	ISRR-3
Mouth and throat discomfort	Included	Included
Palpitations	Included	Included	Included
Cold sweat	Included	Included	Included
Shortness of breathing	Included	Included
Chest pain	Included	Included
Abdominal pain	Included
Nausea	Included
Vomiting	Included
Diarrhea	Included
Vertigo	Included	Included	Included
Syncope	Included	Included	Included
General weakness	Included	Included	Included
Numbness or loss of sensation	Included	Included	Included
Headache	Included	Included	Included
Malaise	Included	Included	Included
Hyperventilation/panic attack	Included	Included	Included
Photophobia	Included	Included	Included
Feeling of hot flush	Included	Included	Included
Vasovagal reflex	Included	Included	Included

Vasovagal reflex included hypotension and/or bradycardia.

ISRR-2, Initial case definition of ISRR without gastrointestinal symptoms;

ISRR-3, initial case definition of ISRR without gastrointestinal and respiratory symptoms.