Table E4.
Participant of immediate hypersensitivity reaction (IHSR) groups in sensitivity analysis
| Demographic characteristic | IHSR-2 |
IHSR-3 |
||||
|---|---|---|---|---|---|---|
| Cases (N = 284) | Controls (N = 1136) | P value | Cases (N = 188) | Controls (N = 752) | P value | |
| Age (y) | ||||||
| >65 | 103 (36.3) | 441 (38.8) | .853 | 74 (39.4) | 324 (43.1) | .610 |
| 51-65 | 63 (22.2) | 237 (20.9) | 42 (22.3) | 147 (19.5) | ||
| 36-50 | 62 (21.8) | 249 (21.9) | 36 (19.1) | 156 (20.7) | ||
| ≤35 | 56 (19.7) | 209 (18.4) | 36 (19.1) | 125 (16.6) | ||
| Sex | ||||||
| Male | 61 (21.5) | 651 (57.3) | <.001 | 44 (23.4) | 446 (59.3) | <.001 |
| Female | 223 (78.5) | 485 (42.7) | 144 (76.6) | 306 (40.7) | ||
| Comorbidities | ||||||
| Hypertension | 40 (14.1) | 148 (13.0) | .626 | 33 (17.6) | 120 (16) | .582 |
| Diabetes | 12 (4.2) | 58 (5.1) | .646 | 8 (11.7) | 42 (5.9) | .587 |
| Dyslipidemia | 16 (5.6) | 54 (4.8) | .541 | 15 (4.3) | 44 (5.6) | .312 |
| Cardiovascular diseases | 4 (1.4) | 39 (3.4) | .082 | 3 (1.6) | 30 (4.0) | .125 |
| Asthma | 20 (7.0) | 16 (1.4) | <.001 | 14 (7.4) | 13 (1.7) | <.001 |
| Atopic dermatitis | 4 (1.4) | 3 (0.3) | .033 | 4 (2.1) | 3 (0.4) | .033 |
| Thyroid diseases | 14 (4.9) | 11 (1.0) | <.001 | 11 (5.9) | 9 (1.2) | <.001 |
| Malignancy | 5 (1.8) | 19 (1.7) | 1.000 | 3 (1.6) | 16 (2.1) | .780 |
| Mental disorders | 6 (2.1) | 19 (1.7) | .615 | 4 (2.1) | 18 (2.4) | 1.000 |
| History | ||||||
| Allergic episodes for drugs | 81 (28.5) | 36 (3.2) | <.001 | 54 (28.7) | 28 (3.7) | <.001 |
| Allergic episodes for foods | 76 (26.8) | 29 (2.6) | <.001 | 49 (26.1) | 20 (2.7) | <.001 |
| Vasovagal episode | 8 (2.8) | 10 (0.9) | .016 | 3 (1.6) | 5 (0.7) | .202 |
| No. of vaccine doses received | ||||||
| First | 189 (66.5) | 756 (66.5) | 1.000 | 128 (68.1) | 512 (68.1) | 1.000 |
| Second | 95 (33.5) | 380 (33.5) | 60 (31.9) | 240 (31.9) | ||
| Period | ||||||
| May 24-June 23 | 90 (31.7) | 360 (31.7) | 1.000 | 72 (38.3) | 288 (38.3) | 1.000 |
| June 24-July 23 | 57 (20.1) | 228 (20.1) | 30 (16.0) | 120 (16.0) | ||
| July 24-August 23 | 80 (28.2) | 320 (28.2) | 50 (26.6) | 200 (26.6) | ||
| August 24-September 24 | 57 (20.1) | 228 (20.1) | 36 (19.1) | 144 (19.1) | ||
Data are presented as n (%).
IHSR-2, Initial case definition without respiratory symptoms; IHSR-3, initial case definition included only clinical signs.