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. 2022 Aug 8;17(8):e0272649. doi: 10.1371/journal.pone.0272649

Table 3. Characteristics of studies regarding social relationships associated with the patient’s affective symptoms.

Author (year) Social relationship (measures) Affective symptoms (measures) Analysis adjusts for Key findings
Functional Aspect of Social Relationships
Social support
Roberts et al.,1994 Social support (SSQ) Psychological status (SCL-90-R) & (distress GSI) Desirability 1) Single patients who had support from friend demonstrated lower depression (r = -0.44), anxiety (r = -0.38), and overall severity of psychological distress (r = -0.41) (all p <0.05).
2) Married patients who had support from spouse demonstrated lower depression (r = -0.27) as well as overall severity of psychological distress (r = -0.27) (both p<0.01).
Neuling et al., 1988 Social support (MDSS) Anxiety
(STAI)
Depression
(Wakefield Self-Assessment Depression Inventory)
NR In hospital,
1) Anxiety was related to amount of support received from friends [F(1,49) = 5.84;p<0.05] and satisfaction with support from family members [F(1,50) = 4.54, p<0.05].
2) Depression was related to the amount of support from friends [F(1,49) = 6.50, p<0.05] and satisfaction with family support [F(1,50) = 5.58, p<0.05].
1-month post operation,
Anxiety was related to the amount of support received from friends [F(1,37) = 6.77, p<0.05)
3-month post operation,
1) Anxiety was not related to the amount of support but was related to satisfaction with support from family [F(1,34) = 9.72, p<0.005]
2) Depression was related to satisfaction with support from family [F(1,34) = 5.60, p<0.05]
Koopman et al., 1998 Social support (Yale Social Support Index & single item measure) Mood disturbance (POMS) NR Patients’ mood disturbances were positively associated with aversive social support.
Lee et al., 2004 Social Support (SSS) Mood disturbance (Linear Analogue Self-Assessment Scale) NR Patients with low social support reported higher mood disturbance (r = -0.25, p = 0.004).
Maly et al., 2005 Emotional &Instrumental support (items developed based on qualitative interview) Depression (CES-D)
Anxiety (STAI-S)
Socio-demographics, cancer stage, treatment type, comorbidity 1) Patients demonstrated lower depressive when they had partners who helped around the house (β = -0.16, p = 0.048).
2) In white women (patients), they showed more anxiety when they had other family members or friends who helped with bathing or dressing (β = 0.20, p = 0.028)
3) In non-white women (patients), their anxiety became lower when they had children who listened to concerns or worries (β = -0.30, p = 0.044) and helped around the house (β = -0.25, p = 0.046).
4) In non-white women (patients), their depression became lower when they had children who helped around the house (β = -0.30, p = 0.02).
Palesh et al., 2006 Social support (UCLA Social Support Inventory) Mood disturbance (POMS) NR No relationship was found between mood disturbances and satisfaction with social support
Porter et al., 2006 Social support satisfaction (SSQ) Negative mood (POMS-SF) NR Patients demonstrated less negative mood state when their satisfaction with social support increased (β = -0.087, t = -2.041).
Friedman et al., 2006 Social support (SSQ) Mood disturbances (TMD and POMS-SF) NR No association was found between mood disturbances and social support
Kim & Morrow, 2007 Family support (FES) Anxiety (STAI) Emetic score Higher family support predicted lower patients’ anxiety level (β = -0.36, p<0.001).
Nausheen & Kamal, 2007 Familial social support (FSSS) Depression (SSDS) NR 1) Patients showed less depression when they had strong familiar support (r = -0.85, p<0.001)
Von Ah & Kang, 2008 Emotional and aid support (NSSQ) Mood disturbance (POMS-SF) NR 1) Emotional support was associated with mood disturbance before (r = -.34, p < .01), after (r = -.47, p < .001) adjuvant therapy.
2) Aid support was associated with mood disturbances during (r = -.38, p < .001) adjuvant therapy.
3) Prior to adjuvant therapy, aid support had indirect effect on mood disturbance whereas emotional support has both indirect (ß = -0.42, p < .05) and direct effect (ß = -0.53) on mood disturbances
4) During adjuvant therapy, aid support has indirect effect of mood disturbance
5) After adjuvant therapy, emotional support has both direct (ß = -0.39, p<0.01) and indirect effects on mood disturbances.
Gellaitry et al., 2010 Social Support (Significant Others Scale) Psychological well-being (POMS) Baseline measures In intervention group, patients demonstrated less depression when they were satisfied with emotional support (p<0.05)
Gorman et al., 2010 Social support (MOS-SSS) Depressive symptoms (CES-D) Demographic and clinical characteristics, randomized assignment Patients with greater social support showed lower depressive symptoms (p<0.0001)
Hasson-Ohayon et al., 2010 Agent of Support and Type of Support (CPASS) Psychological distress (BSI) NR 1) Patients demonstrated lower depression when they had support from spouse (r = -0.16, p<0.05), family (r = -0.28, p<0.01), and friends (r = -0.24, p<0.01).
2) Patients demonstrated lower anxiety when they had support from family (r = -0.22, p<0.01).
3) Higher family support predicted lower patient’s psychological distress (β = -0.32, p<0.005).
4) Higher family support predicted lower depression and anxiety (β = -0.20, p<0.0057; β = -0.19, p<0.052).
Kim et al., 2010 Social support (developed from previous studies using six items) Emotional well-being (FACT-B) Age, education level, race, living status, cancer stage 1) Patients with strong social support reported good emotional well-being (r = .34, p < .001)
2) Social support influenced emotional well-being (ß = 0.23, p < .001)
Talley et al., 2010 Partner social support (Items developed by Alferi et al, 2001) Depression (CES-D) Age, income co-morbid illness, co-residence, distance from radiation treatment center, level of physical symptoms Patients showed lower levels of depression when they had greater partner emotional support (β = -0.23, p<0.05).
Cohen et al., 2010 Perceived social support (self-report 10-item) Emotional distress (BSI-18) Demographics Perceived social support predicted the variance of emotional distress (β = -0.30, p<0.01)
Hill et al., 2011 Perceived emotional support (MOS-SSS) MD (Major depression)
GAD (Generalized anxiety disorder)
History of psychiatric disorder 1) During one year after cancer diagnosis, low social support predicted onset of MD (OR = 2.20, 95%CI = 1.12–4.33, p<0.05)and GAD (OR = 2.51, 95%CI = 1.05–5.97, p<0.03)
2) Low social support predicted the risk of onset of both MD (OR = 3.43, 95% CI = 1.32–8.87, p = 0.01) and GAD (OR = 4.00, 95% CI = 1.42–11.30, p = 0.01)
Lee et al., 2011 Perceived Social Support (MOS-SSS) Depressive Mood (SDS) Demographics, menopausal status, BMI, exercise, drinking status. Worsen emotional support (p<0.001), informational (p = 0.04) were associated with deteriorated depressive mood.
Liu et al., 2011 Social support (social support rating scale) Anxiety and depression (HADS)
Psychological stress (Psychological stress scale)
NR 1) Patients’ psychological stress were associated with social support (subjective and objective) and its utility (all p<0.05)
2) Both anxiety (r = -0.196, p<0.01; r = -0.128, p<0.05) and depression (r = -0.141, p<0.01; r = -0.168, p<0.01) were associated with objective support and its utility.
3) Depression was associated with subjective social support (r = -0.315, p<0.01).
4) Subjective social support (β = -0.108, p<0.05) and its utility (β = 0.329, p<0.05) were predictors of anxiety.
5) Objective social support (β = -0.249, p<0.05) was a predictor of depression
Boinon et al., 2012 Perceived social support (Cancer-specific questionnaire of social support) Depressive symptom (BDI-SF)
Negative affect (PANAS)
Demographics, time since surgery, social sharing variables Patients with higher perceived negative support demonstrated higher depressive symptoms and negative affect (ß = 0.24, p<0.05; ß = 0,26, p<0.01)
Jones et al., 2012 Social support (MSPSS)
Unsupportive social interactions (USII)
Health anxiety (MIHT)
Anxiety and depression (HADS)
Demographics, cancer-related variables, general anxiety and depression 1) Patients had a tendency to worry about their health (health anxiety-affective dimension) when they had unsupportive social interactions (r = 0.36, p<0.001)
2) Patient’s health anxiety-affective dimension was predicted by unsupportive interactions (β = 0.21, p<0.05) and social support (β = -0.20, p<0.05).
3) Patients reported higher anxiety when they had lower perceived social support (r = -0.32, p<0.001) and unsupportive social interactions (r = 0.41, p<0.001)
4) Patients reported higher depression when they had lower perceived social support (r = -0.33, p<0.001) and unsupportive social interactions (r = 0.44, p<0.001)
Mallinckordt et al., 2012 Social support (SPS-M) Psychological distress (BSI) NR 1) Patients demonstrated less psychological distress when they had higher social support (T1:r = -0.26, p<0.01; T2: r = -0.44,p<0.01).
2) A significant association was found between social support and psychological distress at both T1 and T2 (all p<0.01)
Popoola & Adewuya, 2012 Perceived social support (indicating on Likert scale) Depression (MINI) NR 1) Depression was associated with perceived social support (p = 0.001).
2) Perceived poor social support was a significant predictor of depression (β = 1.078, p = 0.014)
Aguado Loi et al., 2013 Social support group attendance (Demographic questionnaire)
Satisfaction with social support (Demographic questionnaire)
Depression (PHQ-9) NR 1) Increased depression was associated with satisfaction with family/peer support (β = -0.42, p<0.01).
2) The amount of support from family and friends was associated with depressive symptoms (β = -0.36, p<0.01).
So et al., 2013 Social support (MOS-SSS) Anxiety and Depression (HADS) None Patients showed lower levels of depression (β = -0.37, p<0.05) and anxiety (β = -0.28, p<0.05) when they had greater social support
Waters et al., 2013 Perceived social support (MOS-SSS) Emotional well-being
(RAND 36-Item Health Survey)
Worry (FACT-B)
Demographics, depression history and trait anxiety,
cancer stage, types of surgical and adjuvant treatments
1) Patients showed higher worrying about cancer progression when they had lower social support (r = 0.16, p<0.05).
2) Patients with higher social support reported better emotional well-being (Wilks’ Λ = l0.86, F[24,1,320] = 2.9, p < .0001)
Yi & Kim, 2013 Social support (PRQ-II) Depressive symptom (CES-D) NR Patients with low social support reported higher depression (r = -.585, p < .0001).
Boinon et al., 2014 Perceived social support (SSQ6) Psychological distress (Impact of Event Scale)
Depressive symptoms (Beck Depression Inventory)
NR 1) A higher level of depressive symptoms at T2 (after adjuvant therapy) was associated with lower quantity of support (r = -.20, p<0.05), instrumental support (r = -0.26, p<0.01), and informational support at T1(before adjuvant therapy) (r = -0.20, p<0.05)
2) Patients who perceived a higher instrumental support at T1 reported a lower level of depressive symptoms (β = -0.27, p<0.05) at T2
Hasson-Ohayon et al., 2014 Social support (CPASS) Psychological distress (BSI) None 1) A significant association was found between social support and depression in younger patient group (β = -0.32, p = 0.016).
2) No significant association was found between social support and depression in older patient group.
Hughes et al., 2014 Social support (ESSI) Depression (CES-D) Demographics, comorbidities, cancer stage, time since treatment Patients with lower social support at T1(prior to cancer treatments) experienced higher level of depressive symptoms from T1 to T2 (6 months after the completion of cancer treatments) (β = -.47, t(137) = -2.97, p = 0.004) than patients with more social support.
Schleife et al., 2014 Social support (VAS) Anxiety and Depression (HADS) NR 1) Patients receiving social support showed less depression (r = -0.43, p<0.01) as well as anxiety (r = -0.36, p<0.01).
2) Higher social support decreased mental distress (β = -0.37, p<0.01).
Wang et al., 2014 Social support (SSRS)
Perceived social support (PSSS)
Depression (CES-D)
Anxiety (STAI)
NR Patients with strong perceived social support (β = -0.29, p<0.01; β = -0.23, p<0.01) and objective social support (β = -0.12, p<0.05; β = -0.14, p<0.05) reported lower depression as well as anxiety
Borstelmann et al., 2015 Perceived social support (MOS-SSS)
Marital subscale of Perceive partner support (CARES)
Anxiety (HADS) NR 1) Unsupported/partnered patients had higher anxiety (p<0.0001)
2) Patients with lower social support (OR = 0.96, 95% CI = 0.95–0.97) and unsupported/partnered (OR = 2.09, 95% CI = 1.34–3.24) reported higher anxiety
Ozkaraman et al., 2015 Social support (CPSSS) Social image anxiety (SIAS) NR 1) Patients demonstrated higher anxiety about body image when they received support from the spouse and/or children, but it was lower among women who had support only from friends (KW = 16.20; p = 0.02)
2) Higher anxiety was associated with decreasing reliance support (r = -0.35, p<0.001)
Alfonsson et al., 2016 Lack of social support (Self-report Questionnaire) Anxiety and Depression (HADS) NR 1) Lack of social support at T1 (shortly after diagnosis) predicted anxiety at T1 (p<0.001).
2) Lack of social support at T1 and T2 predicted anxiety at T2 (3 years after diagnosis) (p = 0.027; p = 0.020).
3) Lack of social support at T1 predicted depression at T1 (p = 0.004).
4) Lack of social support at T1 and T2 predicted depression at T2 (p = 0.01; p = 0.002).
Malicka et al., 2016 Social support (BSSS) Anxiety (STAI) Depression (BDI) NR No association was found between social support and anxiety as well as depression.
Berhili et al., 2017 Family support (ask direct question about family assistance) Anxiety and depression (HADS) Demographics, taking analgesic and/or anxiolytic treatment, current treatment type Patients demonstrated psychological distress when they had lack of social family support (p<0.001)
Fong et al., 2017 Social Support (MOS-SSS) Depressive symptoms (CES-D)
Stress (Perceived Stress Scale)
Positive and Negative Affect (Positive and Negative Affect Schedule)
Demographics, cancer stage 1) Decline in social support quality predicted increase in depression (p = 0.003), negative affect (p = 0.05), and stress (β = -0.22, p = 0.01).
2) Decreases in social support quantity (β = -0.20) predicted increases in stress.
3) No association was found between social support quantity and negative and positive affect.
Moon et al., 2017 Receiving emotional/instrumental support (counting the total number of message containing emotional/instrumental support expression) Depression (CES-D) Demographics, total volume of message 1) Patients who received emotional support by cancer survivors demonstrated greater reduction of depression (β = -0.32, p<0.001).
2) No association was found between receiving emotional support provided by other new patients and the reduction in depression.
Schellekens et al., 2017 Social support (MOS-SSS) Mood disturbances (POMS) NR In MBCR group, patients with increased social support reported changes in their mood disturbances (β = -0.24, p = 0.004)
Su et al., 2017 Family support (APGAR) Psychiatric diagnosis (MINI) NR Higher family support was associated with lower risk for major depressive disorder (β = 0.87, p<0.05).
Thompson et al., 2017 Social support (MOS-SSS) Depressive symptoms (CES-D) Randomization assignment, levels of general health, depressive symptoms at baseline 1) Patients with lower initial levels of social support demonstrated more severe depressive symptoms (β = 0.33, p<0.001)
2) Patients with lower baseline social support (β = -0.20, p<0.05) as well as greater decline in social support (β = -0.40, p<0.05) over time demonstrated more depressive symptoms over time
Tomita et al., 2017 Social support (MOS-SSS) Depressive symptoms (CES-D) NR Higher perceived social support decreased depressive symptoms
(β = -0.25)
Bright & Stanton, 2018 Social support (ISEL-12) Depression (CES-D) Demographics, medical factors, number of children Greater social support at baseline was associated with lower depressive symptoms at 1month after hormone therapy (β = -0.41, p<0.001)
Schmidt et al., 2018 Perceived social support (MSPSS) Affective fatigue (FAQ) Socio-demographics, clinical characteristics Patients with poor social support (p = 0.001) demonstrated increased affective fatigue
Escalera et al., 2019 Social support (MOS-SSS) Psychological distress (BSI-18) Demographics, time since diagnosis, adjuvant breast cancer treatment, cancer stage, history of depression 1) Patients demonstrated fewer depressive symptoms when they had emotional/informational support (β = -0.17, p = 0.01), tangle support (β = -0.12, p = 0.03), positive social interaction (β = -0.13, p = 0.03)
2) Tangible support (β = -0.16, p = 0.006), affectionate support (β = -0.21, p = 0.001), and positive social interaction (β = -0.14, p = 0.02) were negatively associated with anxiety symptoms
Wondimagegnehu et al., 2019 Social support (MSPSS) Depression (PHQ-9) NR Depressed patients were found to have lower social support than non-depressed women (p = 0.027)
Janowski et al., 2020 Social support (Disease-related Social Support Scale) Depression (BDI) NR 1) Women with greater social support demonstrated lower depression than those with lower social support (t = 4.08, p<0.001)
2) Spiritual support was a significant predictor of depressive symptoms (R2 = 0.27, β = -0.52, t = -5.01, p<0.001).
Debretsova &Derakshan., 2021 Social support (MOS-SSS) Anxiety and depression (HADS) NR Patients with greater social support demonstrated lower depression (r = -0.50, p<0.001)
Fisher et al., 2021 Social support (MOS-SSS) Depression (CES-D) Demographics, medical factors Patients with greater social support demonstrated lower depression (emotional support, β = -3.17, p<0.001)
Zamanian et al.,2021 Social support (MOS-SSS) Anxiety (DASS-A) and depression (DASS-D) Demographics, medical factors, spouse’s education, house mates Patients with greater social support demonstrated lower anxiety and depression (r = -0.26~-0.38, p<0.001)
Okati-Aliabad et al., 2022 Social support (MSPSS) Anxiety and depression (HADS) NR Patients with greater social support demonstrated lower depression (r = -0.21,p<0.001)
Social support and /or social constraints
Schmidt & Andrykowski 2004 Social support (DUKE-SSQ)
Social constraints (SCS)
Anxiety and Depression (HADS) NRv 1) Patients with greater social support demonstrated lower depression (β = -0.23, p<0.001)
2) Patients with greater social constraints demonstrated greater depression as well as anxiety (β = 0.31, p<0.001; β = 0.34, p<0.001)
Wong et al., 2018 Social constraints (Social constraints scale)
Social support (Chinese version of MOS-SSS)
Depressive symptoms (CES-D) Demographic, medical variables, cancer stage 1) The indirect effect of social constraints on depressive symptoms through social support was significant (β = 0.11, p<0.01)
2) The direct effect of social support on depressive symptoms was significant (β = -0.28, p<0.01)
Lally et al., 2019 Social constraints Depressive symptoms (CES-D) No covariates 1) Patients who perceived social constraints from family/friends and spouse/partner reported higher depressive symptoms
2) Patients who experienced increased on family/friends social constraints reported no changes in their depressive symptoms (p = 0.049)
3) Patients who experienced decreased family/friends social constraints reported decreased depressive symptoms (p = 0.049)
Social support and family functioning (family conflict and family stress)
Lueboonthavatchai, 2007 Social support (SSQ)
Family functioning (Family relationship and functioning questionnaire)
Anxiety and depression (HADS) NR 1) Patients’ anxiety and depression were associated with social support (p<0.001) and family relationship and functioning (p<0.001).
2) Poor family relationship and functioning was a predictor of anxiety and depression (p<0.05).
Mantani et al., 2007 Family functioning (FAD) Anxiety (Zung self-rating anxiety scale)
Depression (Zung self-rating depression scale)
NR Patients demonstrated higher depression when they perceived inappropriate affective responsiveness among family members (β = 0.59, p<0.01).
Ashing-Giwa et al., 2013 Social support (MOS-social support survey)
Family stress (five-items from Life Stress Scale)
Depressive symptom (CES-D) NR Patients with low social support (r = -.37, p < .01) as well as family stress (r = .522, p = < .01) reported more depressive symptoms
Segrin et al., 2018 Family conflict (Family Assessment Device) Anxiety (PROMIS-Anxiety short form)
Depressive symptoms (CES-D)
NR 1) Patients demonstrated higher depressive symptoms when family conflict was high (β = 0.17, p<0.01)
2) Patients demonstrated higher anxiety when their family conflict was high (β = 0.11, p<0.05)
Quality of relationships
Giese-Davis & Hermanson,
2000
Quality of couple’s relationship (FRI): cohesion, expression, conflict Mood disturbance (POMS) Income Patients demonstrated lower mood disturbance when they rated the relationship (w/partners) greater in cohesion-expression (β = -0.42, p<0.01) as well as greater in conflict (β = -0.40, p<0.001)
Manne et al., 2007 Relationship satisfaction (DAS) Psychological distress (Mental Health Inventory) Sociodemographic, ECOG, surgery type, functional impairment, time since diagnosis, length of relationship Greater patient relationship satisfaction was associated with decreased patients’ psychological distress (β = -0.07, p<0.0001)
Segrin et al., 2007 Relationship satisfaction (RAS) Anxiety (PANAS, SF-12, ICS, and GSDS)
Depression (CES-D)
NR 1) No association was found between patients’ anxiety and her reported relationship quality
2) Higher anxiety was found in patients when their partners reported dissatisfied relationship quality (T1:r = -0.20, p<0.05; T2:r = -0.28, p<0.01; T3:r = -0.27, p<0.05)
Al-Zaben et al., 2015 Marital quality (SPS&QMI) Anxiety and Depression (HADS) NR No significant association was found of anxiety/depression with the quality of the marital relationship
Structural Aspect of Social Relationships
Simpson et al., 2002 Social Integration (ISSSI) Mental Health (SCL&SCID)
Depression (BDI)
Age, group membership, GAF, BDI, and GSI scores, baseline social support score 1) Women who had psychiatric illness assessed by SCID had lower social support (p<0.001).
2) Social integration was not a predictor of the present of psychiatric illness.
3) Social integration (adequacy of close relationships) was a predictor of depression at 1-year post intervention (β = -0.23, p<0.01).
4) Social integration (adequacy of more distant supports) was a predictor of global severity of depression at 1 year post-intervention (β = -0.36, p<0.001).
Both Aspects of Social Relationships
Brothers & Andersen, 2009 Perceived social support (PSS-F)
Social network index (SNI)
Presence of significant other/romantic partner
Depression (CES-D) Physical functioning 1) Depression was not associated with perceived social support
2) Patients’ depression at both initial and follow-up was associated with the presence of support person (r = -0.25, p<0.05; r = -0.44, p<0.05)
3) The presence of significant others (β = -0.26, p<0.01) was a significant predictor of depression at follow-up.
Gagliardi et al., 2009 Social network (Social Network List)
Social support (1 to 4 Likert-type scale)
Anxiety (ASQ)
Depression (CDQ)
NR 1) Patients demonstrated lower anxiety (r = -0.43, p<0.01) and depression (r = -0.35, p<0.05) when they had strong informational support from kins
2) Patients demonstrated lower anxiety when they had strong emotional support (r = -0.356, p<0.05) from kins
3) No association was found between social network and patients’ anxiety and depression
Puigpinos-Riera et al., 2018 Social network (SNI)
Social support (MOS-SS)
Co-habitation at home
Anxiety and depression (HADS) NR 1) High risks of depression and anxiety were associated with social isolation (p = 0.00; p = 0.00) and low social support (p = 0.00; p = 0.00)
2) Living alone was associated with anxiety (p = 0.011).
Wang et al., 2019 Social support (MOS-SSS)
Social network index (count a total number of people who talk at least once every two weeks)
Depression and anxiety (PROMIS-short form) Demographics, the level of acculturation (only for Chinese women), and clinical variables 1) Patients showed more depression and anxiety when they had less social support (all p<0.05)
2) No association was found between social network and patients’ anxiety and depression
Liu et al., 2021 Social support (Social support rating scale)
Social network (social isolation subscale of Lubben’s social network)
Anxiety and depression (HADS) NR 1) Patients with lower social support (r = -0.334, p<0.01) and greater social isolation (r = 0.369, p<0.01) demonstrated greater anxiety.
2) Patients with lower social support (r = -0.289, p<0.01) and greater social isolation (r = 0.466, p<0.01) demonstrated greater depression.

MOS-SSS = Medical Outcomes Survey-Social Support Survey; CARES = Cancer Rehabilitation Evaluation System; HADS = Hospital Anxiety and Depression Scale; SSS = Social Support Scale; CES-D = Center for Epidemiological Studies Depression Scale; PRQ-II = Personal Resource Questionnaire II; FACT-B = Functional Assessment of Cancer Therapy-Breast; POMS = Profile of Mood States; POMS-SF = Profile of Mood States-Short Form; NSSQ = Norbeck Social Support Questionnaire;SSQ6 = Social Support Questionnaire Short Form; STAI = State-Trait Anxiety Inventory; SSRS = Social Support Rating Scale; PSSS = Perceived Social Support Scale; FSSS = Familiar Social Support Scale; SSDS = Siddiqui-Shah Depression Scale; SCS = Social Constraints Scale; ASQ = Anxiety Scale Questionnaire; CDQ = Clinical Depression Questionnaire; MBSR = Mindfulness-Based Stress Reduction; SET = Supportive Expressive Group Therapy; CSOSI = Calgary Symptom of Stress Inventory; PANAS = Positive and Negative Affect Schedule; RAS = Relationship Assessment Scale; MIS = Lewis Mutuality and Interpersonal Sensitivity Scale; FHI = Family Hardiness Index; MDSS = Multi-Dimensional Support Scale; BDI-SF = Beck Depression Inventory-Short Form; DUKE-SSQ = Duke-UNC Functional Social Support Questionnaire; SCS = Social Constraints Scale; FRI = Family Relationship Index; MSPSS = Multidimensional Scale of Perceived Social Support; PHQ-9 = Patient Health Questionnaire 9; DAS = Dyadic Adjustment Scale; FACT-B: Functional Assessment of Cancer Therapy-Breast; BSI = Brief Symptom Inventory; CPASS = Cancer Perceived Agents of Social Support; ESSI = ENRICHD Social Support Instrument; ISEL = Support Evaluation List; SCL-90R: Standard Checklist-90-Revised; GSI = Global Severity Index; FAQ = Fatigue Assessment Questionnaire; MINI = Mini International Neuropsychiatric Interview; APGRA = Adaptability, Partnership, Growth, Affection, and Resolve; SNI = Berkman-Syme Network Index; FES = Family Environment Scale; PROMIS = Patient Reported Outcome Measurement Information System; CPSSS = Cancer Patient’s Social Support Scale; SIAS = Social Image Anxiety Scale; MIHT = Multidimensional Inventory of Hypochondriacal Traits; USII = Unsupportive Social Interactions Inventory; SSQ = Social Support Questionnaire; TMD = Total Mood Disturbance; FACIT-G = Functional Assessment of Chronic Illness Therapy-General; SPS = Spousal Perception Scale; QMI = Quality of Marriage Index; ISEL-12 = Interpersonal Support Evaluation List (12 items); SPS-M: Social Provision Scale-Modified; BSSS = Berlin Social Support Scale; SCID = Structured Clinical Interview for DSM-III-R; VAS = Visual Analogue Scales; ISSB = Inventory of Socially Supportive Behaviors; MISSB = Modified Inventory of Socially Supportive Behaviors; SF-12 = 12-item Short Form Survey; ICS = Index of Clinical Stress; GSDS = General Symptom Distress Scale