TABLE 3.
PRISM Score <10 (n = 211) | PRISM Score 11-20 (n = 58) | PRISM Score >20 (n = 66) | |||||||
---|---|---|---|---|---|---|---|---|---|
Survivors (n = 204) | Nonsurvivors (n = 7) | P value* | Survivors (n = 49) | Nonsurvivors (n = 9) | P value* | Survivors (n = 38) | Nonsurvivors (n = 28) | P value* | |
Favipiravir, n (%) | 84 (41.2) | 4 (57.1) | 0.45 | 29 (59.2) | 7 (77.8) | 0.46 | 21 (55.3) | 19 (67.9) | 0.30** |
Oseltamivir, n (%) | 29 (14.2) | 0 (0) | 0.60 | 5 (10.2) | 1 (11.1) | 0.94 | 7 (18.4) | 2 (7.1) | 0.28 |
Lopinavir/ritonavir, n (%) | 18 (8.8) | 1 (14.3) | 0.49 | 7 (14.3) | 0 (0) | 0.59 | 3 (7.9) | 3 (10.7) | 0.69 |
Remdesivir, n (%) | 16 (7.8) | 0 (0) | 0.46 | 6 (12.2) | 1 (11.1) | 0.92 | 2 (5.4) | 2 (7.1) | 0.58 |
Hydroxychloroquine, n (%) | 34 (16.7) | 0 (0) | 0.60 | 10 (20.4) | 1(11.1) | 0.51 | 10 (26.3) | 6 (21.4) | 0.65† |
Glucocorticoid therapy, n (%) | 83 (40.7) | 3 (42.9) | 0.91 | 28 (57.1) | 7 (77.8) | 0.30 | 23 (60.5) | 18 (64.3) | 0.76† |
IVIG, n (%) | 35 (19.5) | 1 (14.3) | 0.82 | 13 (26.5) | 4 (44.4) | 0.43 | 8 (21.1) | 13 (46.4) | 0.03 † |
Convalescent plasma transfusion, n (%) | 5 (2.5) | 1 (14.3) | 0.19 | 1 (2.0) | 1 (11.1) | 0.29 | 0 (0) | 0 (0) | – |
Anakinra, n (%) | 2 (1.0) | 0 (0) | 0.79 | 0 (0) | 0 (0) | – | 1 (2.6) | 0 (0) | 0.58 |
Colchicine, n (%) | 3 (1.5) | 0 (0) | 0.75 | 0 (0) | 0 (0) | – | 0 (0) | 0 (0) | – |
Tocilizumab, n (%) | 1 (0.5) | 0 (0) | 0.85 | 0 (0) | 0 (0) | – | 1 (2.6) | 0 (0) | 0.58 |
Anticoagulation, n (%) | 96 (47.1) | 3 (42.9) | 0.83 | 28 (57.1) | 7 (77.8) | 0.30 | 24 (63.2) | 19 (67.9) | 0.69† |
Inotrope treatment, n (%) | 14 (6.9) | 6 (85.7) | 0.00 | 12 (24.5) | 9 (100) | 0.00 | 16 (42.1) | 27 (96.4) | 0,00 † |
Renal replacement therapy, n (%) | 1 (0.6) | 1 (14.3) | 0.07 | 1 (2.0) | 6 (66.7) | 0.00 | 1 (2.6) | 7 (25.0) | 0.01 |
Plasma exchange, n (%) | 7 (3.9) | 0 (0) | 0.62 | 5 (10.2) | 4 (44.4) | 0.03 | 2 (5.3) | 4 (14.3) | 0.39 |
Hemadsorption, n (%) | 0 (0) | 0 (0) | - | 0 (0) | 0 (0) | - | 1 (2.6) | 1 (3.6) | 0.67 |
ECMO, n (%) | 0 (0) | 0 (0) | - | 1 (2.0) | 0 (0) | 0.67 | 1 (2.6) | 3 (10.7) | 0.30 |
ECMO indicates extracorporeal membrane oxygenation; IVIG, intravenous immunoglobulin.
Fisher’s Exact Test.
Chi-Square test