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. 2022 Jun 1;41(9):742–750. doi: 10.1097/INF.0000000000003592

TABLE 3.

Treatment and its Effect on Mortality in Different PRISM Score Categories

PRISM Score <10 (n = 211) PRISM Score 11-20 (n = 58) PRISM Score >20 (n = 66)
Survivors (n = 204) Nonsurvivors (n = 7) P value* Survivors (n = 49) Nonsurvivors (n = 9) P value* Survivors (n = 38) Nonsurvivors (n = 28) P value*
Favipiravir, n (%) 84 (41.2) 4 (57.1) 0.45 29 (59.2) 7 (77.8) 0.46 21 (55.3) 19 (67.9) 0.30**
Oseltamivir, n (%) 29 (14.2) 0 (0) 0.60 5 (10.2) 1 (11.1) 0.94 7 (18.4) 2 (7.1) 0.28
Lopinavir/ritonavir, n (%) 18 (8.8) 1 (14.3) 0.49 7 (14.3) 0 (0) 0.59 3 (7.9) 3 (10.7) 0.69
Remdesivir, n (%) 16 (7.8) 0 (0) 0.46 6 (12.2) 1 (11.1) 0.92 2 (5.4) 2 (7.1) 0.58
Hydroxychloroquine, n (%) 34 (16.7) 0 (0) 0.60 10 (20.4) 1(11.1) 0.51 10 (26.3) 6 (21.4) 0.65
Glucocorticoid therapy, n (%) 83 (40.7) 3 (42.9) 0.91 28 (57.1) 7 (77.8) 0.30 23 (60.5) 18 (64.3) 0.76
IVIG, n (%) 35 (19.5) 1 (14.3) 0.82 13 (26.5) 4 (44.4) 0.43 8 (21.1) 13 (46.4) 0.03
Convalescent plasma transfusion, n (%) 5 (2.5) 1 (14.3) 0.19 1 (2.0) 1 (11.1) 0.29 0 (0) 0 (0)
Anakinra, n (%) 2 (1.0) 0 (0) 0.79 0 (0) 0 (0) 1 (2.6) 0 (0) 0.58
Colchicine, n (%) 3 (1.5) 0 (0) 0.75 0 (0) 0 (0) 0 (0) 0 (0)
Tocilizumab, n (%) 1 (0.5) 0 (0) 0.85 0 (0) 0 (0) 1 (2.6) 0 (0) 0.58
Anticoagulation, n (%) 96 (47.1) 3 (42.9) 0.83 28 (57.1) 7 (77.8) 0.30 24 (63.2) 19 (67.9) 0.69
Inotrope treatment, n (%) 14 (6.9) 6 (85.7) 0.00 12 (24.5) 9 (100) 0.00 16 (42.1) 27 (96.4) 0,00
Renal replacement therapy, n (%) 1 (0.6) 1 (14.3) 0.07 1 (2.0) 6 (66.7) 0.00 1 (2.6) 7 (25.0) 0.01
Plasma exchange, n (%) 7 (3.9) 0 (0) 0.62 5 (10.2) 4 (44.4) 0.03 2 (5.3) 4 (14.3) 0.39
Hemadsorption, n (%) 0 (0) 0 (0) - 0 (0) 0 (0) - 1 (2.6) 1 (3.6) 0.67
ECMO, n (%) 0 (0) 0 (0) - 1 (2.0) 0 (0) 0.67 1 (2.6) 3 (10.7) 0.30

ECMO indicates extracorporeal membrane oxygenation; IVIG, intravenous immunoglobulin.

*

Fisher’s Exact Test.

Chi-Square test