Table 3.
No evidence for LOH in CHEK2 c.485A>G/p.D162G or c.1100delC/p.T367Mfs carriers.
| CHEK2 variant carriers | Tissue type | VAF c.485A>G | VAF c.1100delC |
|---|---|---|---|
| c.485A>G/p.D162G carrier 1 (brother 1) | Tumor tissue | 0.521 | |
| Control tissue | 0.482 | ||
| c.485A>G/p.D162G carrier 2 (brother 2) | Tumor tissue | 0.526 | |
| Control tissue | 0.476 | ||
| c.1100delC/p.T367Mfs carrier 1 | Tumor tissue | 0.538 | |
| Control tissue | 0.485 | ||
| c.1100delC/p.T367Mfs carrier 2 | Tumor tissue | 0.466 | |
| Control tissue | N/A |
Note: VAF refers to variant allele frequency.
Abbreviation: N/A, not available.