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. 2022 Jul 8;11(15):2969–2977. doi: 10.1002/cam4.4796

TABLE 3.

TLS density and maturity in different groups

TLS density(p value) TLS maturity (Grade I II III) (p value)
Sex(F/M) 0.458 ± 0.09/0.351 ± 0.08(0.0545) 91–41‐87/55–17‐7 (0.360)
Age(60+/60‐) 0.335 ± 0.05/0.528 ± 0.132(0.0336) 78–36‐9/68–22‐6 (0.508)
Smoking(Y/N) 0.442 ± 0.16/0.418 ± 0.07(0.6179) 19–8‐6/123–50‐9 (0.051)
EGFR mutation(Y/N) 0.415 ± 0.06/0.434 ± 0.32(0.0598) 115–52‐13/31–6‐2 (0.218)
Pathological types
MIA/AIS 0.443 ± 0.28/0.216 ± 0.23(0.6343) 27–5‐2/3–1‐0 (0.629)
IAC/AIS 0.420 ± 0.06/0.216 ± 0.23(0.2694) 116–52‐13/3–1‐0 (1.000)
MIA/IAC 0.443 ± 0.28/0.420 ± 0.06(0.1346) 27–5‐2/116–52‐13 (0.213)
CT features
pGGN/mGGN 0.178 ± 0.06/0.522 ± 0.12(0.0001) 26–7‐1/67–28‐9 (0.397)
pGGN/SN 0.178 ± 0.06/0.388 ± 0.08(0.0003) 26–7‐1/53–23‐5 (0.587)
mGGN/SN 0.522 ± 0.12/0.388 ± 0.08(0.0526) 67–28‐9/53–23‐5 (0.813)
Tumor stages 0.183 0.026
IA1‐IA3 0.399 ± 0.03 130–45‐14
IB‐IIB 0.533 ± 0.14 15–13‐1

p < 0.05 was considered significant.

Abbreviations: AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; IAC, invasive adenocarcinoma; pGGN, pure ground‐glass nodule; PSN, part‐solid nodule; SN, solid nodule.