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. 2022 Jul 23;135:104328. doi: 10.1016/j.ijnurstu.2022.104328

Table 2.

Professional and individual factors and health risk behaviors associated with major depression (dependent variable) in 10,325 healthcare workers.

Characteristics Univariate model
Multivariate model
No major depression
7203(69.8%)
Major depression
3122(30.2%)
p-value Adjusted odds ratio
(aOR) (95% IC)
p-value
Individual factors
Age (years) 42.13(10.92) 42.60(10.66) 0.151 1.005(1.001–1.005) 0.015
Sex(man) 1265(17.6%) 724 (23.2%) < 0.0001 1.771(1.539–2.038) < 0.0001
Partner at home 49(15.0%) 41(17.4%) < 0.0001 0.638(0.563–0.723) < 0.0001
Children at home 4288(59.5%) 1764(56.5%) 0.004 0.983(0.563–0.723) 0.779
Family caregiver 1188(16.5%) 688(22.0%) < 0.0001 1.230(1.073–1.410) 0.003
History of recurrent major depression 617(6.0%) 892(8.6%) < 0.0001 2.778(2.407–3.207) < 0.0001
Chronic illness 1041(14.5%) 633(20.3%) < 0.0001 1.078(0.933–1.244) 0.308



Professional factors
Public sector vs. private sector 6152(85.4%) 2764(88.5%) < 0.0001 1.172(0.997–1.378) 0.089
Full-time job 5961(82.8%) 2669(85.5%) 0.001 0.985(0.845–1.149) 0.849
Night shift work 442(6.1%) 206(6.6%) 0.374
Job content questionnaire dimensions
 Speed and quantity 8.37(2.00) 9.36(1.99) < 0.0001 0.973(0.938–1.008) 0.126
 Complexity and intensity 8.73(1.63) 9.59(1.60) < 0.0001 1.095(1.048–1.145) < 0.0001
 Fragmentation and unpredictability 8.47(2.04) 9.50(1.89) < 0.0001 1.082(1.045–1.119) < 0.0001
 Decision-making latitude 37.63(6.42) 33.77(7.55) < 0.0001 0.978(0.969–0.987) < 0.0001
 Use of skills 17.30(2.91) 16.44(3.19) < 0.0001 0.992(0.971–1.013) 0.461
 Skill development 19.70(2.96) 18.51(3.45) < 0.0001 0.999(0.979–1.020) 0.922
 Professional support by superiors 5.48(1.66) 4.64(1.75) < 0.0001 0.937(0.859–1.022) 0.140
 Professional support by colleagues 6.48(1.11) 4.64(1.75) < 0.0001 1.037(0.968–1.110) 0.301
 Emotional support by superiors 5.50(1.72) 4.65(1.83) < 0.0001 1.000(0.921–1.086) 0.996
 Emotional support by colleagues 6.45(1.16) 5.89(1.42) < 0.0001 0.853(0.801–0.909) < 0.0001
Work schedules characteristics
 Random schedules 3344(46.4%) 1546(49.5%) 0.004 1.135(1.017–1.267) 0.024
 Working longer than expected at least once a week 4533(62.9%) 2245(71.9%) < 0.0001 1.178(1.076–1.384) 0.013
Burnout 3088(42.9%) 2624(84.0%) < 0.0001 4.826(4.291–5.428) < 0.0001
Absenteeism 1212(16.8%) 845(27.1%) < 0.0001 1.440(1.276–1.626) < 0.0001



Professional violence at the workplace
 Sustained bullying at the workplace 2397(33.3%) 1712(54.8%) < 0.0001 1.343(1.197–1.506) < 0.0001
 Sexual harassment exposure 476(6.6%) 280(9.0%) < 0.0001 1.023(0.835–1.252) 0.828
 Sexual orientation-based discrimination 406(5.6%) 248(7.9%) < 0.0001 1.052(0.850–1.304) 0.640



Health risk behaviors
Overweight/obesity 2504(34.8%) 1222(39.1%) < 0.0001 0.976(0.871–1.093) 0.669
Daily tobacco smoking ≥ 20 cigarettes/day 113(1.6%) 134(4.3%) < 0.0001 1.473(1.069–2.031) 0.018
Hazardous drinking 1112(15.4%) 813(26.0%) < 0.0001 1.548(1.356–1.767) < 0.0001
Moderate to high physical activity 4714(65.5%) 1678(53.8%) < 0.0001 0.743(0.666–0.828) < 0.0001
Sleep duration (hours) 6.81(1.19) 6.15(1.35) < 0.0001 0.700(0.669–0.732) < 0.0001

Significant associations (p < 0.05) are in bold.

Adjusted for all variables associated with major depression with p < 0.2 in univariate analyses.