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. 2022 Jun 20;14(8):958–963. doi: 10.1038/s41557-022-00945-w

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© The Author(s) 2022, corrected publication 2022

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Fig. 1 — Schematic of a cell-sized microfluidic droplet, containing multi-functional DNA-based filaments. The DNA-based filaments undergo dynamic assembly and disassembly triggered by strand-displacement reactions or aptamer–target interactions. Moreover, apparent guided directional transport of organic lipid membrane vesicles or inorganic gold nanoparticles along the filament tracks is powered by ribonuclease H (RNase H)-mediated hydrolysis.