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Mendelian randomization estimation of serum metabolites on the risk of 4 primary cancers by inverse-variance weighted analysis, grouped according to known and unknown metabolites. OCa, ovarian cancer; BCa, breast cancer; BCa(ER−), ER-negative breast cancer; BCa(ER+), ER-positive breast cancer; LUADC, lung adenocarcinoma; LCa, lung cancer; LUSCC, lung squamous cell carcinoma.
