Table 2. Clinical characteristics of patients in TCGA-LUAD dataset and the three independent GEO datasets.
| Clinical features | TCGA-LUAD | GSE72094 | GSE50081 | GSE31210 |
|---|---|---|---|---|
| Samples sizes | 293 | 386 | 130 | 204 |
| Age (years), mean ± SD | 64.86±9 | 71.5±1.5 | 61.83±1.745 | 48±10 |
| Follow time (days), mean ± SD | 740.94±627.5 | 1,439±190 | 1,510.55±8.578 | 1,201.5±458.5 |
| Survival status, n | ||||
| Death | 83 | 109 | 54 | 30 |
| Survival | 210 | 277 | 76 | 174 |
| Sex, n | ||||
| Male | 131 | 168 | 67 | 95 |
| Female | 162 | 218 | 63 | 109 |
| Stage, n | ||||
| I | 162 | 246 | 93 | 162 |
| II | 62 | 65 | 37 | 42 |
| III | 47 | 56 | ||
| IV | 15 | 14 | ||
| Unknown | 7 | |||
| Smoking status, n | ||||
| Ever | 291 | 94 | 99 | |
| Never | 30 | 23 | 105 | |
| Unable to determine | 65 | 13 | ||
| Kras status, n | ||||
| Wt | 254 | |||
| Mut | 132 | |||
| Tp53 status, n | ||||
| Wt | 290 | |||
| Mut | 96 | |||
| Stk11 status, n | ||||
| Wt | 323 | |||
| Mut | 63 |
TCGA, The Cancer Genome Atlas; LUAD, lung adenocarcinoma; GEO, Gene Expression Omnibus; SD, standard deviation; Wt, wild-type; Mut, mutated.