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. 2022 Aug 8;5:794. doi: 10.1038/s42003-022-03759-1

Table 1.

Summary of QPI drug response parameters.

Name Abbreviation Description Units
Specific growth rate SGR Exponential growth constant, computed as the rate of change of cell mass over time, normalized by cell mass h−1
Half maximal effective concentration EC50 Therapy concentration at which cells exhibit 50% of maximum response µM
Depth of response DoR Maximum difference in SGR between cells at minimum and maximum therapy concentrations, computed from Hill sigmoid curve fitting parameters -
Time of response ToR The average time required to elicit a response to therapy at the tested concentration h
Standard deviation of response SD Standard deviations of SGR at the tested concentration as a measure of cell-to-cell heterogeneity h−1