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. 2022 Aug 8;12:321. doi: 10.1038/s41398-022-02085-8

Fig. 1. Structural covariance network of the ventral visual stream and acute PTSD severity.

Fig. 1

Linked independent components analysis (LICA) was completed on fractional anisotropy (FA), mean diffusivity (MD), mode of the diffusion tensor (MO), gray matter volume (GMV), cortical thickness (CT), and pial surface area (PSA) spatial maps to derive multimodal components. We observed a component that reflected a structural analog of the ventral visual stream derived from all participants (A). The component predominantly reflected FA, GMV, and PSA of the visual cortex, anterior temporal lobe, and the inferior fronto-occipital fasciculus (left) and the distribution of loadings across participants (right) (B). The component was related to total scores on the PTSD Checklist for DSM-5 (PCL-5) in both full (left) and parsimonious (right) models described in the “Methods” section (C). Brain figures represent the ventral visual stream structural covariance network obtained from LICA across all participants. Scatter plots are partial plots where dots represent the standardized residuals of individual participant loadings and PCL-5 scores. Lines represent the linear line of best fit and the shaded bar represents the 95% confidence interval.