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. 2022 Aug 8;13(8):693. doi: 10.1038/s41419-022-05138-4

Fig. 6. Specific deletion of Gsdmd in neutrophils instead of macrophages protected the kidney from undergoing fibrosis after UUO.

Fig. 6

A Representative images of Masson trichrome staining of kidney sections. Kidneys were collected from Gsdmdfl/fl, Gsdmdwt/wtLyzcre, Gsdmdfl/flLyzcre, Gsdmdwt/wtMpr8cre and Gsdmdfl/flMpr8cre mice on day 13 after UUO. Scale bar: 100 μm. B, C Representative images of immunofluorescence staining of kidney sections, showing the expression of α-SMA B and Col I C. DAPI (blue) was used for nuclear staining. Scale bar: 100 μm. D–F Quantification of renal fibrosis scores evaluated by Masson trichrome staining D, α-SMA E, and Col I F expression by immunofluorescence. n = 6. **P < 0.01.