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. 2022 Jul 6;12(9):2187–2206. doi: 10.1007/s13346-022-01203-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Within laboratory standard deviation of the three individual partner laboratories for three organic nanoparticles tested in the LDH release cell death assay. For each of the three partner laboratories BMTZ, RIVM, and SINTEF, standard deviation was plotted for the LDH release cell death assay. A grayscale heatmap was applied to illustrate variability of results from combinations of organic nanoparticle concentration, cell lines, and cytotoxicity assay