Table 2.
Sural Nerve Harvest and Cell Transplantation Data for Participants Undergoing ahSC Transplantation
| Subject ID | Time Post-injury (years) | Nerve harvest to transplant (weeks) | Nerve length (cm) | Estimated dose based on imaging ( × 106 cells) | Actual dose ( × 106 cells) | Injections (#) | Duration of injections (min:sec) | Rate (μL/min) | Rate (μL/min) | Cell viability (%) | Endotoxin (EU/kg) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 102 | 15 | 15 | 14.5 | 25 | 23 | 2 | 9:00 | ∼30 | 97.1 | 96.6 | 0.0200 |
| 107 | 1 | 15 | 13.0 | 43 | 50 | 2 | 10:00 | ∼50 | 97.7 | 97.1 | 0.0075 |
| 111 | 10 | 15 | 14.0 | 17 | 20 | 1 | 4:00 | ∼50 | 98.7 | 95.1 | 0.0001 |
| 113 | 2 | 15 | 15.0 | 54 | 20 | 2 | 7:17 | ∼30 | 97.4 | 96.2 | 0.0070 |
| 115 | 7 | 15 | 15.0 | 80 | 31 | 3 | 8:56 | ∼40 | 97.4 | 96.3 | 0.0260 |
| 119 | 5 | 16 | 14.0 | 120 | 75 | 3 | 11:43 | ∼63 | 97.3 | 93.9 | 0.0180 |
| 120 | 8 | 36* | 15.0 | 30 | 30 | 1 | 6:00 | ∼50 | 98.8 | 94.3 | 0.0060 |
| 123 | 2 | 15 | 12.0 | 35 | 34 | 3 | 10:40 | ∼35 | 96.5 | 95.6 | 0.0030 |
*
Pre-transplant time extended due to modification of injection system.