Mass spectrometry analysis: detection of ACTR2 (ARP2) and ACTR3 (ARP2) as an exclusive partner of nuclear BRAFV600E. A: BCPAP, BCPAP-empty vector, BCPAP-BRAFV600E, and BCPAP-BRAFV600E-3X NLS were subjected to mass spectrometry analysis, and the 142 unique partners of nuclear BRAF were selected. B: 142 unique proteins were subjected to KEGG and reactome analysis. C: 142 proteins were segregated b/ased on their gen ontology (GO); cellular component (CC), molecular function (MF), and biological process (BP) analyses.