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. 2022 Jul 15;12(7):3318–3332.

Figure 3.

Figure 3

Validation of the 8-gene signature. The time-dependent ROC and Kaplan-Meier curves for evaluating the performance of the 8-gene signature in the validation datasets, DFKZ 2018 (A), GSE107299 (B), and GSE70769 (C). (D) Comparison of the 8-gene signature with three commercial panels using ROC analyses for predicting 1-, 2- and 3-year BFS. (E) The nomogram plot for predicting 1-, 2- and 3-year BFS in PCa patients. (F) The calibration curves of the nomogram showing the probability of BFS at 1-, 2- and 3-year after radical prostatectomy. (G) The DCA curves comparing the net clinical benefit among all significant clinical factors, including the nomogram. ROC: receiver operating characteristic; BFS: biochemical recurrence-free survival; DCA: decision curve analysis.