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A brief scheme of cardiac hypertrophy development and the key molecules mentioned in this review. Ang II, angiotensin II; Ca, calcium; CaMKII, calcium/calmodulin dependent protein kinase; Endo 1, Endothelin 1; GATA, GATA binding protein; HDAC, histone deacetylase; ISO, isoproterenol; MEF, myocyte-specific enhancer factor; NFAT, nuclear factor of activated T cells.
