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. 2022 Jul;11(7):982–995. doi: 10.21037/tau-22-428

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2022 Translational Andrology and Urology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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GLP increased the T and cGMP levels in DMED rats. ELISA results showing the levels of T, LH, and FSH in the serum and cGMP in the penile tissue after GLP treatment. ^@@P<0.01 vs. NC; **P<0.01 vs. MC. The results were presented as the mean ± standard deviation. n=6. NC, normal control; MC, model control; GLP-L, GLP low dose; GLP-H, GLP high dose; GLP, Ganoderma lucidum polysaccharide; T, testosterone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; cGMP, cyclic guanosine monophosphate; DMED, diabetes mellitus-induced erectile dysfunction; ELISA, enzyme-linked immunosorbent assay.