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. 2022 Jul;11(7):982–995. doi: 10.21037/tau-22-428

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2022 Translational Andrology and Urology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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GLP prevented the increase in cell apoptosis in the penile tissue of DMED rats. (A) Representative image of TUNEL assay and quantification of the apoptosis index after GLP treatment (×400). (B) Representative images of the caspase-3 and caspase-9 proteins assessed by immunohistochemistry (×400). ^@@P<0.01 vs. NC; **P<0.01 vs. MC. The results were presented as the mean ± standard deviation. n=6. NC, normal control; MC, model control; GLP-L, GLP low dose; GLP-H, GLP high dose; GLP, Ganoderma lucidum polysaccharide; TUNEL, terminal deoxynucleotidyl transferase dUTP nick-end labeling; DAPI, 4',6-diamidino-2-phenylindole; DMED, diabetes mellitus-induced erectile dysfunction.