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. 2022 Jul 26;13:912029. doi: 10.3389/fphar.2022.912029

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Copyright © 2022 Geng, Xu, Zhao, Zhang, Li, Jin, Li, Li, Yang, Li, Gao, Cai, Mao, Sun, Liu, Xu, Wei and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Elevated fibrotic and SASP protein expression in senescent macrophages. (A) IL-1β, IL-6, TNF-α and TGF-β1 expressions by western blot. (B) MMP2, MMP9 and MMP12 expressions by western blot. (C) Immunofluorescence staining for TGF-β1. (D) Immunofluorescence staining for MMP12. Data are presented as the mean ± SD. n = 3 per group.