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. 2022 Jul 26;13:912029. doi: 10.3389/fphar.2022.912029

FIGURE 8.

FIGURE 8

SiO2 significantly elevated fibrotic and SASP protein expression levels in the lung tissue of silicosis model. (A) IL-1β, IL-6, TNF-α and TGF-β1 expression levels were detected by western blot. (B) MMP2, MMP9 and MMP12 expression levels were detected by western blot. (C) Immunohistochemistry staining for TGF-β1 in the lung. (D) Immunofluorescence staining for MMP12 in the lung. Data are presented as the mean ± SD. n = 3 per group.