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Stem cell effects via EVs in an organoid model. As shown in the picture, the three major subgroups of Evs include microvesicles, exosomes, and apoptotic bodies. Since the stem cells are very dynamic, they can obtain Evs such as exosomes [129]. According to the mentioned applications of EVs, they can be used as nanoparticles in organoid models to make them more efficient [130, 131]. EVs: extracellular vesicles
