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. 2022 Jul 15;14(7):4838–4847.

Table 5.

Crude and adjusted ORs of the associations between T1DM and the different lipid profile values and inflammatory and endothelial dysfunction biomarkers

Case Control Crude ORs Adjusted ORs#


ORs 95% CI p-value ORs 95% CI p-value
Lipid profile Values
    HDL 1.56 1.23 1.99 <0.001 1.82 1.39 2.38 <0.001
    LDL 0.92 0.73 1.14 0.437 0.90 0.71 1.13 0.354
    TG 1.43 1.13 1.81 0.003 1.44 1.12 1.83 0.004
    TC 2.18 1.65 2.88 <0.001 2.23 1.67 2.96 <0.001
    ApoA 4.56 3.12 6.67 <0.001 5.23 3.47 7.90 <0.001
    ApoB 2.47 1.84 3.31 <0.001 2.52 1.86 3.40 <0.001
    ApoA/ApoB 1.08 0.87 1.35 0.480 1.12 0.89 1.42 0.331
Liver Enzyme
    GGT 0.24 0.17 0.35 <0.001 0.21 0.14 0.32 <0.001
    ALT 1.65 1.28 2.12 <0.001 1.62 1.25 2.12 <0.001
Inflammatory Biomarkers
    IL-6 1.47 1.16 1.86 0.001 1.48 1.16 1.87 0.001
    Adiponectin 1.43 1.13 1.80 0.003 1.60 1.24 2.06 0.000
    TNF-α 1.21 0.97 1.52 0.089 1.16 0.90 1.49 0.257
    hs-CRP 1.57 1.24 1.98 0.000 1.58 1.24 2.01 <0.001
Endothelial Dysfunction Biomarkers
    ICAM-1 1.79 1.41 2.27 <0.001 1.80 1.40 2.30 <0.001
    VCAM-1 1.36 1.08 1.71 0.010 1.39 1.09 1.77 0.007
    Selectin 0.47 0.36 0.63 <0.001 0.47 0.35 0.63 <0.001
    ET-1 0.32 0.23 0.44 <0.001 0.32 0.23 0.44 <0.001
#

Adjusted for age, gender and BMI.