Table 5.
Crude and adjusted ORs of the associations between T1DM and the different lipid profile values and inflammatory and endothelial dysfunction biomarkers
Case Control | Crude ORs | Adjusted ORs# | ||||||
---|---|---|---|---|---|---|---|---|
|
|
|||||||
ORs | 95% CI | p-value | ORs | 95% CI | p-value | |||
Lipid profile Values | ||||||||
HDL | 1.56 | 1.23 | 1.99 | <0.001 | 1.82 | 1.39 | 2.38 | <0.001 |
LDL | 0.92 | 0.73 | 1.14 | 0.437 | 0.90 | 0.71 | 1.13 | 0.354 |
TG | 1.43 | 1.13 | 1.81 | 0.003 | 1.44 | 1.12 | 1.83 | 0.004 |
TC | 2.18 | 1.65 | 2.88 | <0.001 | 2.23 | 1.67 | 2.96 | <0.001 |
ApoA | 4.56 | 3.12 | 6.67 | <0.001 | 5.23 | 3.47 | 7.90 | <0.001 |
ApoB | 2.47 | 1.84 | 3.31 | <0.001 | 2.52 | 1.86 | 3.40 | <0.001 |
ApoA/ApoB | 1.08 | 0.87 | 1.35 | 0.480 | 1.12 | 0.89 | 1.42 | 0.331 |
Liver Enzyme | ||||||||
GGT | 0.24 | 0.17 | 0.35 | <0.001 | 0.21 | 0.14 | 0.32 | <0.001 |
ALT | 1.65 | 1.28 | 2.12 | <0.001 | 1.62 | 1.25 | 2.12 | <0.001 |
Inflammatory Biomarkers | ||||||||
IL-6 | 1.47 | 1.16 | 1.86 | 0.001 | 1.48 | 1.16 | 1.87 | 0.001 |
Adiponectin | 1.43 | 1.13 | 1.80 | 0.003 | 1.60 | 1.24 | 2.06 | 0.000 |
TNF-α | 1.21 | 0.97 | 1.52 | 0.089 | 1.16 | 0.90 | 1.49 | 0.257 |
hs-CRP | 1.57 | 1.24 | 1.98 | 0.000 | 1.58 | 1.24 | 2.01 | <0.001 |
Endothelial Dysfunction Biomarkers | ||||||||
ICAM-1 | 1.79 | 1.41 | 2.27 | <0.001 | 1.80 | 1.40 | 2.30 | <0.001 |
VCAM-1 | 1.36 | 1.08 | 1.71 | 0.010 | 1.39 | 1.09 | 1.77 | 0.007 |
Selectin | 0.47 | 0.36 | 0.63 | <0.001 | 0.47 | 0.35 | 0.63 | <0.001 |
ET-1 | 0.32 | 0.23 | 0.44 | <0.001 | 0.32 | 0.23 | 0.44 | <0.001 |
Adjusted for age, gender and BMI.