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. 2022 Jul 15;14(7):5014–5023.

Figure 5.

Figure 5

Effect of repeated (7 days) administration of ESAF with ARS [(50, 100, 250 mg/kg and combination group p.o (EASF 50 mg/kg+Imipramine 5 mg/kg) + ARS] on GSH-PX levels: Each column represents the mean ± S.E.M. Statistical analysis was performed by one-way ANOVA, followed by Dunnet’s multiple comparison test. *P<0.05, **P<0.01, **P<0.001 as compared to ARS control group. EASF 50 mg/kg for 7 days significantly increased the activity of GSH-PX enzyme in the hippocampus of mice subjected to ARS; F [(6, 35) = 32.33, P<0.001)]. Dunnet’s comparison test also revealed that ESAF 100 mg/kg (P<0.0115) and 250 mg/kg (P<0.0044) significantly increased the activity of GSH-PX and the combination group showed an even more highly significant effect (P<0.0025) when compared to other two doses. ARS: Acute restraint stress; ESAF: Ethanolic Extract of S. asoca Flowers.