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. 2022 Jul 15;14(7):5164–5177.

Table 5.

Changes of complementary area of residue on the modified peptides to HLA

No. Before Residue Replacement-Position-After Residue Replacement Peptide Sequences Surface Complementarity Buried SASA


Before Residue Replacement After Residue Replacement Differences of Replacement Before Residue Replacement After Residue Replacement Differences of Replacement
1 L4Y CYSYYGTTL 0.67 0.87 0.2 0.553 0.423 -0.13
2 T7Y CYSLYGYTL 0.89 0.74 -0.15 0.586 0.647 0.061
3 C1H HYSLYGTTL 0.8 0.74 -0.06 0.848 0.863 0.015
4 S3H CYHLYGTTL 0.84 0.66 -0.18 0.955 0.942 -0.013
5 L9F CYSLYGTTF 0.8 0.83 0.03 0.981 0.977 -0.004
6 Y2W CWSLYGTTL 0.79 0.83 0.04 0.976 0.976 0
7 L9W CYSLYGTTW 0.8 0.77 -0.03 0.981 0.962 -0.019
8 I4Y HYNYVTFCC 0.56 0.85 0.29 0.335 0.373 0.038
9 V5Y HYNIYTFCC 0.7 0.36 -0.34 0.851 0.336 -0.515
10 F7Y HYNIVTYCC 0.75 0.81 0.06 0.972 0.731 -0.241
11 N3H HYHIVTFCC 0.87 0.86 -0.01 0.977 0.982 0.005
12 C9F HYNIVTFCF 0.69 0.87 0.18 0.916 0.991 0.075
13 Y2W HWNIVTFCC 0.77 0.82 0.05 0.992 0.996 0.004
14 C9W HYNIVTFCW 0.69 0.87 0.18 0.916 0.975 0.059