Table 5.
Changes of complementary area of residue on the modified peptides to HLA
| No. | Before Residue Replacement-Position-After Residue Replacement | Peptide Sequences | Surface Complementarity | Buried SASA | ||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| Before Residue Replacement | After Residue Replacement | Differences of Replacement | Before Residue Replacement | After Residue Replacement | Differences of Replacement | |||
| 1 | L4Y | CYSYYGTTL | 0.67 | 0.87 | 0.2 | 0.553 | 0.423 | -0.13 |
| 2 | T7Y | CYSLYGYTL | 0.89 | 0.74 | -0.15 | 0.586 | 0.647 | 0.061 |
| 3 | C1H | HYSLYGTTL | 0.8 | 0.74 | -0.06 | 0.848 | 0.863 | 0.015 |
| 4 | S3H | CYHLYGTTL | 0.84 | 0.66 | -0.18 | 0.955 | 0.942 | -0.013 |
| 5 | L9F | CYSLYGTTF | 0.8 | 0.83 | 0.03 | 0.981 | 0.977 | -0.004 |
| 6 | Y2W | CWSLYGTTL | 0.79 | 0.83 | 0.04 | 0.976 | 0.976 | 0 |
| 7 | L9W | CYSLYGTTW | 0.8 | 0.77 | -0.03 | 0.981 | 0.962 | -0.019 |
| 8 | I4Y | HYNYVTFCC | 0.56 | 0.85 | 0.29 | 0.335 | 0.373 | 0.038 |
| 9 | V5Y | HYNIYTFCC | 0.7 | 0.36 | -0.34 | 0.851 | 0.336 | -0.515 |
| 10 | F7Y | HYNIVTYCC | 0.75 | 0.81 | 0.06 | 0.972 | 0.731 | -0.241 |
| 11 | N3H | HYHIVTFCC | 0.87 | 0.86 | -0.01 | 0.977 | 0.982 | 0.005 |
| 12 | C9F | HYNIVTFCF | 0.69 | 0.87 | 0.18 | 0.916 | 0.991 | 0.075 |
| 13 | Y2W | HWNIVTFCC | 0.77 | 0.82 | 0.05 | 0.992 | 0.996 | 0.004 |
| 14 | C9W | HYNIVTFCW | 0.69 | 0.87 | 0.18 | 0.916 | 0.975 | 0.059 |