TABLE 1.

The role of PVN and glutamatergic system in PVN during Bezold-Jarisch reflex responses.

	Kainic acid (KA) – PVN microinjection				Kynurenic acid (Kyn) – PVN microinjection
	Pre	Post			Pre	Post
	5 min	5 min	20 min	30 min	5 min	5 min	20 min	30 min
ΔMAP	−51.7 ± 7.3	−29.2 ± 7.4*	−24.0 ± 10.1*	−44.2 ± 6.8	−40.0 ± 8.7	−19.0 ± 3.4*	−27.7 ± 7.7	−38.0 ± 8.4
ΔHR	−115.0 ± 24.3	−54.5 ± 10.2*	−42.0 ± 20.5*	−73.7 ± 15.9	−71.2 ± 10.7	−22.5 ± 4.8*	−63.0 ± 27.4	−76.2 ± 29.4

Values are expressed as mean ± SEM. *Significantly different compared with pre-microinjection [p < 0.05, post-KA vs. pre-KA (n = 4) and post-Kyn vs. pre-Kyn (n = 4)].

ΔMAP, change in mean arterial pressure; ΔHR, change in heart rate.