Table 2.
Electrocardiographic and Echocardiographic Findings of the Study Population
| Total (n = 89) | FSHD Group (n = 35) | Control Group (n = 54) | P | |
|---|---|---|---|---|
| Heart rate, beat/min | 87 (77-92) | 87 (80-93) | 86 (76-92) | .751 |
| QRS duration, ms | 88.5 (82.0-96.0) | 85.5 (76.2-96.0) | 89.5 (84.0-95.7) | .165 |
| QT duration, ms | 345 (325-360) | 341 (316-359) | 349 (331-366) | .220 |
| Corrected QT duration, ms | 401 (382-423) | 389 (373-406) | 417 (396-428) | .001 |
| Fragmented QRS, n (%) | 6 (6.7) | 3 (8.5) | 3 (5.6) | .634 |
| Brunch blocks, n (%) | 9 (10.1) | 7 (20.0) | 2 (3.7) | .017 |
| LV diastolic diameter, mm | 4.5 (4.2-4.7) | 4.4 (4.2-4.6) | 4.6 (4.3-4.8) | .020 |
| LV systolic diameter, mm | 2.7 (2.4-2.9) | 2.6 (2.3-2.7) | 2.7 (2.6-2.9) | .002 |
| Septum thickness, mm | 9 (8-10) | 9 (8-11) | 9 (8-10) | .770 |
| LV posterior wall thickness, mm | 9 (8-10) | 9 (8-10) | 9 (8-10) | .616 |
| LV diastolic volume index, mL/m2 | 56.44 (50.12-61.42) | 55.73 (44.63-59.71) | 56.97 (52.27-61.83) | .078 |
| LV systolic volume index, mL/m2 | 19.84 (18.06-22.03) | 19.77 (17.21-21.91) | 19.85 (18.55-22.28) | .483 |
| Biplane ejection fraction, % | 64.0 (63.0-66.0) | 64.0 (63.0-66.0) | 64.0 (62.8-66.0) | .813 |
| Mitrale E wave, cm/s | 0.90 (0.79-0.98) | 0.83 (0.73-0.95) | 0.91 (0.83-1.03) | .014 |
| Mitrale A wave, cm/s | 0.66 (0.56-0.80) | 0.63 (0.54-0.71) | 0.68 (0.58-0.83) | .058 |
| Lateral e wave, cm/s | 18.0 (14.0-21.0) | 16.0 (12.0-19.0) | 19.0 (16.0-22.0) | <.001 |
| Lateral a wave, cm/s | 10.0 (8.0-11.0) | 10.0 (8.0-11.0) | 10.0 (9.0-12.0) | .040 |
| Lateral Sm, cm/s | 9.0 (8.0-11.0) | 9.0 (8.0-13.0) | 9.5 (8.0-11.0) | .879 |
| Septal e wave, cm/s | 14.0 (12.0-16.5) | 13.0 (10.0-16.0) | 15.0 (13.0-17.0) | .009 |
| Septal a wave, cm/s | 9.0 (8.0-11.0) | 8.0 (7.0-10.0) | 9.0 (9.0-11.0) | .026 |
| Septal Sm, cm/s | 9.0 (8.0-10.0) | 8.0 (8.0-10.0) | 9.0 (8.8-10.0) | .052 |
| Apical 4 chamber LS, % | −19.7[(−21.1)-(−18.3)] | −19.9[(−21.6)-(−17.6)] | −19.7[(−21.1)-(−18.6)] | .605 |
| Apical 2 chamber LS, % | −20.1[(−22.1)-(−18.9)] | −19.9[(−21.8)-(−18.2)] | −20.4[(−22.2)-(−19.4)] | .305 |
| Apical 3 chamber LS, % | −19.8[(−21.7)-(−18.5)] | −19.2[(−20.6)-(−18.2)] | −19.9[(−21.8)-(−18.7)] | .150 |
| LV-GLS, % | −20.0[(−21.2)-(−18.9)] | −19.8[(−21.2)-(−18.4)] | −20.1[(−21.5)-(−19.0)] | .259 |
| LV GLS-endocardium,% | −23.1[(−24.7)-(−21.7)] | −22.8[(−24.8)-(−20.8)] | −23.2[(−24.6)-(−21.8)] | .364 |
| LV GLS-epicardium, % | −17.5[(−18.9)-(−16.5)] | −17.1[(−18.3)-(−15.4)] | −17.8[(−19.2)-(−16.7)] | .104 |
| LV-GCS, % | −21.1[(−22.4)-(−19.6)] | −20.3[(−22.0)-(−19.0)] | −21.6[(−22.5)-(−20.0)] | .020 |
| LV-GRS, % | 43.6 (38.3-47.8) | 42.3 (38.3-47.3) | 45.3 (38.8-48.6) | .338 |
| RV EDA, cm2 | 15.9 (13.9-19.2) | 15.1 (13.6-18.2) | 16.8 (15.5-19.9) | .033 |
| RV ESA, cm2 | 8.8 (7.5-10.2) | 8.1 (7.5-10.2) | 9.1 (7.7-10.8) | .208 |
| RV FAC, % | 45.8 (42.0-48.3) | 44.5 (41.1-46.6) | 46.5 (42.2-49.1) | .055 |
| TAPSE, mm | 22 (20-24) | 22 (19-25) | 22 (21-23) | .446 |
| RV-GLS total, % | −23.5[(−25.7)-( −20.9)] | −22.7[(−27.1)-( −19.4)] | −23.7[(−25.4)-( −21.7)] | .250 |
| RV free wall longitudinal strain, % | −28.0[(−31.1)-( −24.0)] | −26.2[(−32.0)-( −22.4)] | −28.2[(−30.0)-( −25.9)] | .288 |
Continuous variables are presented given as median (interquartile range), and categorical variables were expressed as numbers (%). EDA, end diastolic area; ESA, end systolic area; FAC, fractional area change; GCS, global circumferential strain; GLS, Global longitudinal strain; GRS, global radial strain; LS, layer strain; LV, left ventricle; RV, right ventricle; Sm, peak systolic velocity at myocardial segments; TAPSE, tricuspid annular plane systolic excursion.
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