Table 1. Association of Independent SNVs in the Human Leukocyte Antigen Locus With Hodgkin Lymphoma Susceptibility.
SNV | Positionc | Allele | Unconditional logistic regression | Conditional logistic regressiona | Conditional logistic regressionb | ||||
---|---|---|---|---|---|---|---|---|---|
Risk | Other | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | ||
rs28383311 | 32619234 | A | T | 1.80 (1.59-2.03) | 2.14 × 10−21 | NA | NA | NA | NA |
rs3129198 | 33103045 | A | G | 1.54 (1.39-1.72) | 2.64 × 10−15 | 1.53 (1.37-1.70) | 2.05 × 10−14 | NA | NA |
rs3129890 | 32446496 | T | C | 1.23 (1.10-1.37) | 1.71 × 10−4 | 1.48 (1.32-1.65) | 7.04 × 10−12 | 1.51 (1.35-1.69) | 6.21 × 10−13 |
Abbreviaitons: NA, not applicable; OR, odds ratio; SNV, single-nucleotide variant.
Conditional on rs28383311 and rs3129198.
Conditional on rs28383311.
Position according to human reference Genome Reference Consortium Human Build 38.