Skip to main content
. 2022 Aug 8;5(8):e2225647. doi: 10.1001/jamanetworkopen.2022.25647

Table 2. Association of HLA Alleles With Hodgkin Lymphoma Susceptibility.

Marker ID Positiona Allele Imputed Zb r2predc Imputed P value
Effect Other
HLA_DQB1_0603 32631061 Presence Absence 6.48 0.82 9.35 × 10−11
HLA_DQB1_0602 32631061 Presence Absence 6.08 0.88 1.17 × 10−9
HLA_DQB1_06 32631061 Presence Absence 5.71 0.92 1.14 × 10−8
HLA_DQB1_0501 32631061 Presence Absence –5.54 0.97 3.07 × 10−8
HLA_DQB1_05 32631061 Presence Absence –5.87 0.92 4.41 × 10−9
HLA_DQB1_0301 32631061 Presence Absence 5.81 0.88 6.08 × 10−9
HLA_DRB1_1501 32552064 Presence Absence 5.84 0.89 5.28 × 10−9
HLA_DPB1_10 33049368 Presence Absence 5.49 0.51 4.07 × 10−8
HLA_DPB1_1001 33049368 Presence Absence 5.49 0.51 4.07 × 10−8

Abbreviation: HLA, human leukocyte antigen.

a

Postion refers to the genomic coordinates based on Genome Reference Consortium Human Build 37.

b

Z scores represent association with Hodgkin lymphoma.

c

The r2pred values represent the assessment of the imputation reliability at each HLA variant.