Table 3. Association of SNVs in Non–Human Leukocyte Antigen Regions With Hodgkin Lymphoma Susceptibility Based on Meta–Genome-Wide Association Studies.
| SNV | Positiona | Neighboring genes | Allele | OR (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Risk | Other | |||||
| rs1432297 | chr2:60843517 | REL | G | A | 1.29 (1.18-1.41) | 2.50 × 10−08 |
| rs2757647 | chr6:135446416 | AH1 | T | C | 1.30 (1.18-1.42) | 3.52 × 10−08 |
| rs13279159 | chr8:128150801 | PVT1 | G | A | 1.33 (1.20-1.47) | 1.74 × 10−08 |
| rs3824662 | chr10:8062245 | GATA3 | C | A | 1.52 (1.33-1.73) | 3.86 × 10−10 |
| rs117953624 | chr11:104438259 | PDGFD | C | T | 1.98 (1.56-2.51) | 1.45 × 10−08 |
Abbreviations: OR, odds ratio; SNV, single-nucleotide variant.
a
Position according to human reference Genome Reference Consortium Human Build 38.