A, Early time-restricted eating plus energy restriction (eTRE+ER) was more effective than the control eating schedule plus energy restriction (CON+ER) for losing weight. Data shown are least-squares means and 95% CIs from linear mixed modeling with adjustment for age, sex, and race. There were no statistically significant differences between groups for body fat (B), fat-free mass (C), or the ratio of fat loss to weight loss (nā=ā41) (D). Data shown in panels B-D are means and 95% CIs from multiple imputation by chained equations, followed by linear regression with adjustment for age, sex, and race.