TABLE 3.
Cytologic features of Salivary Gland Carcinoma with High-Grade Transformation in Previous Studies
Histology | Diagnostic Category | Cytologic Diagnosis | Cell Component | Nuclear Pleomorphism | Prominent Nucleoli | High Nuclear/Cytoplasmic Ratio | Background | |
---|---|---|---|---|---|---|---|---|
González-Peramato et al10 | AcCC-HGT | Malignant | Salivary carcinoma, AcCC, and high-grade carcinoma | LG + HG | Present | Present | Present | Lymphoid |
Malhotra et al11 | AdCC-HGT | Malignant | Adenocarcinoma NOS, undifferentiated carcinoma | LG + HG | Present | Present | Present | Hemorrhagic |
Johnykutty et al12 | AcCC-HGT | Malignant | High-grade salivary gland neoplasm | LG + HG | Present | Present | Present | NS |
Suzuki et al13 | EMC-HGT | Malignant | NS | LG + HG | Present | Present | NS | NS |
Jung et al14 | SC-HGT | Malignant | NS | HG only | Present | Present | Present | Clear |
Bhardwaj et al15 | AdCC-HGT | Malignant | Poorly differentiated carcinoma | LG + HG | Present | Present | NS | Necrotic, myxoid matrix |
Dutta et al16 | AdCC-HGT | Malignant | Basaloid neoplasm, AdCC/basal cell adenocarcinoma | Presumably LG only | Absent | Absent | Present | NS |
Pusztaszeri et al17 | AdCC-HGT | Malignant | AdCC-HGT | LG + HG | Present | Present | NS | Histiocytic, lymphoid |
Abbreviations: AcCC, acinic cell carcinoma; AdCC, adenoid cystic carcinoma; EMC, epithelial-myoepithelial carcinoma; HG, high-grade component; HGT, high-grade transformation; LG, low-grade component; NOS, not otherwise specified; NS, not stated; SC, secretory carcinoma.