Fig. 1.

Incidence of the combined endpoint (composite of death, admission to ICU/IMC, and/or invasive ventilation) in the overall populations (upper panel) and in hospitalized patients (lower panel) stratified by sex (left) or tertiles of gender (right). Data (bar graphs) are presented as incidence rates of the composite outcome and 95% confidence interval (CI). For each population, the prognostic value of biological sex and gender (as competing co-variates) for the combined endpoint are depicted. Models (tables) were adjusted for patient baseline characteristics including symptoms at presentation, pre-existing conditions, medications, anthropometric data, clinical and laboratory data and presented as odds ratio (OR) and 95% confidence interval (CI). Clinical biological predictors (left side) and sociocultural predictors (right side) of the combined endpoint selected by our multivariable models are also depicted. CVRFs cardiovascular risk factors, WBC white blood cells, ASAT aspartate aminotransferase, MAP mean arterial pressure, ICU intensive care unit, IMC intermediate care unit