NCT04742049.

Study name	The effects of telerehabilitation on muscle function, physical activity and sleep in cystic fibrosis during pandemic
Methods	Design: single‐centre, parallel‐design, RCT Location: Hacettepe University, Ankara, Turkey Duration: 6 weeks
Participants	Enrolment goal: 30 participants with CF Inclusion criteria: people diagnosed with CF; volunteering to participate in the study; in social isolation due to COVID‐19 pandemic; FEV1 > 40% at last pulmonary function test Exclusion criteria: acute pulmonary exacerbation at the time of study or within the last month (or both); diagnosis of COVID‐19 before or during study; being physically or perceptually competent to exercise [sic]; ABPA treated with systemic steroid therapy; inability to complete the exercise training; FEV1 < 40% predicted
Interventions	This study evaluates the effects of a telerehabilitation‐based exercise programme versus usual care in participants who are at home during the self‐isolation process due to the COVID‐19 pandemic. Intervention group: an online 6‐week training programme includes 30 min of exercise performed 3 days per week, supervised by a physiotherapist. Training will start with warm‐up and finish with cool‐down exercises. Control group: receives same exercise document including the same exercise protocol. Participants will be called by the physiotherapist once a week for follow‐up.
Outcomes	Primary outcomes 1‐min sit to stand test repetitions, measured at baseline and after 4 and 6 weeks Crunch repetitions, measured at baseline and after 4 and 6 weeks Squat repetitions, measured at baseline and after 4 and 6 weeks Push‐up repetitions, measured at baseline and after 4 and 6 weeks Plank duration, measured at baseline and after 4 and 6 weeks Secondary outcomes Sleep quality will be evaluated by Epworth Sleepiness Scale and Pediatric Sleep Questionnaire, measured at baseline and after 6 weeks Physical activity level assessed with the Physical Activity Questionnaire at baseline and after 6 weeks
Starting date	28 December 2020
Contact information	Kubra Kilic, PhD Student: Hacettepe University, Ankara, Turkey; telephone: +903123051576 (+903123051576 University); Email: fztktas@gmail.com
Notes	5 different outcome measures were defined as primary endpoints. Single blinding of participants is mentioned on ClinicalTrials.gov. It is not clear to the review authors how participants can be blinded to exercise training/no exercise training in this study setting.